Browsing by Author "Al-Dhfyan, Abdullah"
Now showing items 1-3 of 3
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Epigenetic Regulations of Cancer Stem Cells by the Aryl Hydrocarbon Receptor Pathway
Sabah, Akhtar; Hourani, Shireen; Therachiyil, Lubna; Al-Dhfyan, Abdullah; Agouni, Abdelali; Zeidan, Asad; Uddin, Shahab; Korashy, Hesham M.... more authors ... less authors ( Elsevier , 2020 , Article)Compelling evidence has demonstrated that tumor bulk comprises distinctive subset of cells generally referred as cancer stem cells (CSCs) that has been proposed as a strong sustainer and promoter of tumorigenesis and ... -
In vivo and in vitro studies evaluating the chemopreventive effect of metformin on the aryl hydrocarbon receptor-mediated breast carcinogenesis
Ali, Alhoshani; Alotaibi, Moureq; As Sobeai, Homood M.; Alharbi, Naif; Alhazzani, Khalid; Al-Dhfyan, Abdullah; Alanazi, Fawaz E.; Korashy, Hesham M.... more authors ... less authors ( Elsevier , 2021 , Article)Metformin (MET) is a clinically used anti-hyperglycemic agent that shows activities against chemically-induced animal models of cancer. A study from our laboratory showed that MET protectes against 7, 12-dimethylbenz[a]anthracene ... -
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Fawaz E., Alanazi; As Sobeai, Homood M.; Alhazzani, Khalid; Al-Dhfyan, Abdullah; Alshammari, Musaad A; Alotaibi, Moureq; Al-hosaini, Khaled; Korashy, Hesham M.; Alhoshani, Ali... more authors ... less authors ( Elsevier , 2021 , Article)Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) ...