Browsing by Author "Younes H.M."
Now showing items 1-5 of 5
-
New three-dimensional poly(decanediol-co-tricarballylate) elastomeric fibrous mesh fabricated by photoreactive electrospinning for cardiac tissue engineering applications
Ismail H.M.; Zamani S.; Elrayess M.A.; Kafienah W.; Younes H.M. ( MDPI AG , 2018 , Article)Reactive electrospinning is capable of efficiently producing in situ crosslinked scaffolds resembling the natural extracellular matrix with tunable characteristics. In this study, we aimed to synthesize, characterize, and ... -
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
Alemrayat B.; Elhissi A.; Younes H.M. ( Taylor and Francis Ltd , 2019 , Article)Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ... -
Preparation and optimization of monodisperse polymeric microparticles using modified vibrating orifice aerosol generator for controlled delivery of letrozole in breast cancer therapy
Alemrayat B.; Elrayess M.A.; Alany R.G.; Elhissi A.; Younes H.M. ( Taylor and Francis Ltd. , 2018 , Article)Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. In this work, and for the first time, using vibrating orifice aerosol generator (VOAG) technology, monodisperse ... -
Retinal cell regeneration using tissue engineered polymeric scaffolds
Abedin Zadeh M.; Khoder M.; Al-Kinani A.A.; Younes H.M.; Alany R.G. ( Elsevier Ltd , 2019 , Article Review)Degenerative retinal diseases, such as age-related macular degeneration (AMD), can lead to permanent sight loss. Although intravitreal anti-vascular endothelial growth factor (VEGF) and steroid injections are effective for ... -
Synthesis, characterization & cytocompatibility of poly (diol-co-tricarballylate) based thermally crosslinked elastomers for drug delivery & tissue engineering applications
HassounaY.M.; ZamaniS.; KafienahW.; YounesH.M. ( Elsevier Ltd , 2018 , Article)The aim of this study was to investigate the synthesis and in vitro characterization of thermoset biodegradable poly (diol-co-tricarballylate) (PDT) elastomeric polymers for the purpose of their use in implantable drug ...