Browsing by Author "Salem, Muhammad"
Now showing items 1-2 of 2
-
Genetic polymorphism effect on warfarin–rifampin interaction: A case report and review of literature
Salem, Muhammad; Eljilany, Islam; El-Bardissy, Ahmed; Elewa, Hazem ( Dove Medical Press , 2021 , Article)Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. ... -
Warfarin-Rifampin-Gene (WARIF-G) Interaction: A Retrospective, Genetic, Case–Control Study
Salem, Muhammad; El-Bardissy, Ahmed; Elshafei, Mohamed Nabil; Khalil, Ahmed; Mahmoud, Hesham; Fahmi, Amr Mohamed; Kasem, Mohamed; Bader, Loulia; Sherbash, Mohamed; Elawady, Mostafa Ibrahim; Abdalazim, Walaa; Howady, Faraj; Elewa, Hazem... more authors ... less authors ( Wiley-Blackwell , 2023 , Article)Warfarin is extensively metabolized by cytochrome P450 2C9 (CYP2C9). Concomitant use with the potent CYP2C9 inducer, rifampin, requires close monitoring and dosage adjustments. Although, in theory, warfarin dose increase ...