Browsing by Subject "Bioavailability"
Now showing items 1-7 of 7
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Determination of glafenine in dosage forms and serum by thin layer densitometry and high performance liquid chromatography
( Elsevier , 1997 , Article)New thin layer densitometry and high performance liquid chromatography (HPLC) methods are described for quantitative determination of glafenine in dosage forms in the presence of its photo-degradation products and in serum ... -
Development of a biocompatible creatinine-based niosomal delivery system for enhanced oral bioavailability of clarithromycin
( Taylor and Francis Ltd , 2016 , Article)Context: Nonionic surfactant vesicles have gained increasing scientific attention for hydrophobic drugs delivery due to their biocompatibility, stability and low cost. Objective: The aim of the present study was to synthesize ... -
Epinephrine in anaphylaxis: Preclinical study of pharmacokinetics after sublingual administration of taste-masked tablets for potential pediatric use
( MDPI AG , 2018 , Article)Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to ... -
Improved bioavailability of poorly soluble drugs through gastrointestinal muco-adhesion of lipid nanoparticles
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Gastrointestinal absorption remains indispensable in the systemic delivery of most drugs, even though it presents several challenges that, paradoxically, may also provide opportunities that can be exploited to achieve ... -
Novel formulation for co-delivery of cinnamon- and cumin-loaded polymeric nanoparticles to enhance their oral bioavailability
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Nanobiotechnology has been an encouraging approach to improving the efficacy of hydrophobic bioactive compounds. The biologically active constituents present in herbal extracts are poorly absorbed, resulting in loss of ... -
Piroxicam loaded polymer hybrid microspheres based tablets with modified release kinetics: Development, characterization and in vivo evaluation
( Pakistan Journal of Pharmaceutical Sciences , 2021 , Article)Piroxicam (PC) is a non-steroidal anti-inflammatory drug characterized by poor aqueous solubility and reported to cause and impart crucial GIT irritation, bleeding, peptic and duodenal ulcer. Engineering of PC ... -
Prospects of Curcumin Nanoformulations in Cancer Management
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)There is increasing interest in the use of natural compounds with beneficial pharmacological effects for managing diseases. Curcumin (CUR) is a phytochemical that is reportedly effective against some cancers through its ...