Browsing by Subject "biomarker"
Now showing items 1-7 of 7
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Computational Analysis Reveals Distinctive Interaction of miRNAs with Target Genes in the Pathogenesis of Chronic Kidney Disease
( MDPI , 2023 , Article)The regulation of genes is crucial for maintaining a healthy intracellular environment, and any dysregulation of gene expression leads to several pathological complications. It is known that many diseases, including kidney ... -
Fascin in Gynecological Cancers: An Update of the Literature
( MDPI , 2021 , Article)Fascin is an actin-binding protein that is encoded by the gene (located on chromosome 7). It triggers membrane projections and stimulates cell motility in cancer cells. Fascin overexpression has been described in different ... -
High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder
( Frontiers Media SA , 2023 , Article)Introduction: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by defects in two core domains, social/communication skills and restricted/repetitive behaviors or interests. There is no approved ... -
Novel biomarkers for potential risk stratification of drug induced liver injury (DILI): A narrative perspective on current trends
( Lippincott Williams and Wilkins , 2019 , Article)Background:Drug induced liver injury (DILI) is an increasing cause of acute liver injury especially with increasing need for pharmacotherapy of widening comorbidities amongst our ever-aging population. Uncertainty however ... -
Osteopontin: A Promising Therapeutic Target in Cardiac Fibrosis
( NLM (Medline) , 2019 , Article)Osteopontin (OPN) is recognized for its significant roles in both physiological and pathological processes. Initially, OPN was recognized as a cytokine with pro-inflammatory actions. More recently, OPN has emerged as a ... -
The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer.
( MDPI , 2019 , Article)Colorectal cancer (CRC) is one of the most common cancers worldwide, with high morbidity and mortality rates. A number of factors including modulation of the tumor microenvironment, high metastatic capability, and resistance ... -
Unveiling a Biomarker Signature of Meningioma: The Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
( MDPI , 2023 , Article Review)Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation into advanced grades classified by World Health Organization (WHO) into Grades 1 to 3. Meningiomas’ ...