Browsing by Subject "homocysteine"
Now showing items 1-3 of 3
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A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway
( De Gruyter , 2019 , Article)High homocysteine levels in Alzheimer's disease (AD) result from low activity of the trans-sulfuration pathway. Glutathione levels are also low in AD. L-cysteine is required for the synthesis of glutathione. The synthesis ... -
Analysis of the Qatari R336C Cystathionine β-Synthase Protein in Mice.
( Wiley , 2019 , Article)Classical homocystinuria is a recessive inborn error of metabolism caused by mutations in the cystathionine beta-synthase (CBS) gene. The highest incidence of CBS deficiency in the world is found in the country of Qatar ... -
Intended and Unintended Benefits of Folic Acid Fortification—A Narrative Review
( MDPI , 2023 , Article)Inadequate folate intake during pregnancy is the leading cause of the development of neural tube defects (NTDs) in newborns. For this reason, mandatory fortification of folic acid, a synthetic, easily bioavailable form, ...