Browsing by Subject "iPSCs"

Now showing items 1-3 of 3

    • CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs 

      Swaidan, Nuha T.; Soliman, Nada H.; Aboughalia, Ahmed T.; Darwish, Toqa; Almeshal, Ruba O.; ... more authors ( Frontiers Media SA , 2024 , Article)
      Reprogramming human somatic cells into a pluripotent state, achieved through the activation of well-defined transcriptional factors known as OSKM factors, offers significant potential for regenerative medicine. While OSKM ...

    • Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs 

      Salloum-Asfar, Salam; Abdulla, Sara A.; Taha, Rowaida Z.; Thompson, I. Richard; Emara, Mohamed M. ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem ...

    • The march of pluripotent stem cells in cardiovascular regenerative medicine. 

      Abou-Saleh, Haissam; Zouein, Fouad A; El-Yazbi, Ahmed; Sanoudou, Despina; Raynaud, Christophe; ... more authors ( BMC , 2018 , Article Review)
      Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and mortality. Heart failure remains a major contributor to this mortality. Despite major therapeutic advances over the past decades, a ...