Browsing by Subject "infection"

Now showing items 1-9 of 9

    • Bioactive Antimicrobial Peptides: A New Weapon to Counteract Zoonosis. 

      Zupin, Luisa; Santos-Silva, Carlos André Dos; Al Mughrbi, Aya R Hamad; Vilela, Livia Maria Batista; Benko-Iseppon, Ana Maria; ... more authors ( MDPI , 2022 , Article Review)
      Zoonoses have recently become the center of attention of the general population and scientific community. Notably, more than 30 new human pathogens have been identified in the last 30 years, 75% of which can be classified ...

    • Editorial: Immune-Modulatory Effects of Vitamin D 

      Zughaier, Susu M.; Lubberts, Erik; Bener, Abdulbari ( Frontiers Media , 2020 , Other)
      Vitamin D plays an essential role in bone development. However, recent studies are beginning to uncover its role as a modulator of the immune system (1). Several reports have shown associations between vitamin D deficiency ...

    • Efficacy and Safety of Colistin versus Tigecycline for Multi-Drug-Resistant and Extensively Drug-Resistant Gram-Negative Pathogens—A Meta-Analysis 

      Abushanab, Dina; Nasr, Ziad G.; Al-Badriyeh, Daoud ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Background: We intended to compare the efficacy and safety outcomes of colistin versus tigecycline as monotherapy or combination therapy against multi-drug resistant (MDR) and extensively drug-resistant (XDR) pathogens. ...

    • Identification of a Histone Deacetylase: Epigenetic Impact on Host Gene Expression. 

      Zughaier, Susu M; Rouquette-Loughlin, Corinne E; Shafer, William M ( MDPI , 2020 , Article)
      Epigenetic reprogramming in macrophages is termed trained innate immunity, which regulates immune tolerance and limits tissue damage during infection. is a strict human pathogen that causes the sexually transmitted infection ...

    • An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels 

      De Leon, Jose; Schoretsanitis, Georgios; Smith, Robert L.; Molden, Espen; Solismaa, Anssi; ... more authors ( Thieme , 2022 , Article)
      This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug ...

    • Prophylactic antibiotics for preventing genital tract infection in women undergoing surgical procedures for incomplete abortion: a systematic review and meta-analysis of randomized controlled trials. 

      Islam, Nazmul; Furuya-Kanamori, Luis; Mahmood, Sadia; Thalib, Lukman ( Wiley , 2020 , Article)
      Findings about the effect of prophylactic antibiotics in preventing genital tract infection (GTI) associated with surgical procedures used for incomplete abortions are conflicting. Some reported a decrease in infection ...

    • Pyocyanin pigment from Pseudomonas aeruginosa modulates innate immune defenses in macrophages 

      Mahgoub, Yasmine; Arif, Rida; Zughaier, Susu ( Qatar University Press , 2021 , Poster)
      Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen. The gram-negative bacillus, commonly associated with hospital-acquired infections, utilizes the host's impaired immune responses to establish ...

    • SARS-CoV-2 Short-Time Infection Produces Relevant Cytopathic Effects in Vero E6 Cell Line. 

      Zupin, Luisa; Fontana, Francesco; Gratton, Rossella; Milani, Margherita; Clemente, Libera; ... more authors ( MDPI , 2021 , Article)
      Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is mainly transmitted through respiratory droplets from positive subjects to susceptible hosts or by direct contact with an infected individual. Our study ...

    • Severity, Criticality, and Fatality of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Beta Variant 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; ... more authors ( Oxford Academic , 2021 , Article)
      Beta (B.1.351) variant COVID-19 disease was investigated in Qatar. Compared to Alpha (B.1.1.7) variant, odds of progressing to severe disease were 1.24-fold (95% CI: 1.11-1.39) higher for Beta. Odds of progressing to ...