Browsing by Subject "Tuberculosis"
Now showing items 1-10 of 10
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A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
( Springer International Publishing , 2016 , Article Review)Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ... -
Comparability of Interviewer-Administration Versus Self-Administration of the Functional Assessment of Chronic Illness Therapy-Tuberculosis (FACIT-TB) Health-Related Quality of Life Questionnaire in Pulmonary Tuberculosis Patients
( Adis , 2016 , Article)Objective To investigate the extent to which two different modes of administration (interview by a trained interviewer versus self-administration) yielded a comparable estimate of health-related quality of life (HRQL) in ... -
Factors affecting patients' compliance to anti-tuberculosis treatment in Yemen
( Blackwell Publishing Ltd , 2013 , Article)Objectives To identify the risk factors associated with patient non-compliance to anti-tuberculosis treatment among Yemini tuberculosis (TB) patients. Methods A prospective nested case-control study was conducted. ... -
Fixed-dose combination associated with faster time to smear conversion compared to separate tablets of anti-tuberculosis drugs in patients with poorly controlled diabetes and pulmonary tuberculosis in Qatar
( BioMed Central Ltd. , 2018 , Article)Background: Diabetes is associated with increased risk of tuberculosis (TB) treatment failure, death, and relapse compared to patients without diabetes. Current TB regimens are available as fixed dose combination (FDC) and ... -
Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq
( Elsevier, Ltd , 2015 , Article)Summary ObjectivesTo determine how tuberculosis (TB) treatment affects the health-related quality of life (HRQL) of patients with pulmonary TB and to identify the predictors of favourable TB treatment outcomes in Baghdad, ... -
Impact of connecting tuberculosis directly observed therapy short-course with smoking cessation on health-related quality of life
(2012 , Article)Background: With evolving evidence of association between tuberculosis (TB) and tobacco smoking, recommendations for the inclusion of tobacco cessation interventions in TB care are becoming increasingly important and more ... -
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic.
( BMC , 2020 , Article)Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ... -
Macrophage Infection by Mycobacteria
( OMICS International , 2016 , Article)Mycobacterium tuberculosis is the etiological agent of tuberculosis. It is a pathogen that continues to draw international concerns particularly due to the emergence of multi-drug resistance and to the difficulties ... -
Nanodiagnostics for tuberculosis detection
( Taylor & Francis , 2017 , Article)Introduction Tuberculosis (TB) is a leading killer worldwide. End TB strategy aims at ending the TB epidemic by 2030. Early, accurate, and affordable diagnosis represents a cornerstone to achieve this goal. Innovative ... -
Targeted delivery of rifampicin to tuberculosis-infected macrophages: design, in-vitro, and in-vivo performance of rifampicin-loaded poly(ester amide)s nanocarriers
( Elsevier B.V. , 2016 , Article)We have developed a nano drug delivery system for the treatment of tuberculosis (TB) using rifampicin (RF) encapsulated in poly(ester amide)s nanoparticles (PEA-RF-NPs), which are biocompatible polymers. In this study, ...