Browsing by Subject "Type 2 diabetes"
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Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
Cardiac autonomic neuropathy: A progressive consequence of chronic low-grade inflammation in type 2 diabetes and related metabolic disorders
( MDPI , 2020 , Article Review)Cardiac autonomic neuropathy (CAN) is one of the earliest complications of type 2 diabetes (T2D), presenting a silent cause of cardiovascular morbidity and mortality. Recent research relates the pathogenesis of cardiovascular ... -
A Delphi consensus study introducing a Problem And attRibutes‐bAsed DIabetes self‐manaGeMent (PARADIGM) intervention for patients with type 2 diabetes
( Elsevier , 2022 , Article)AimEncouraging patients to improve their self-management behavior based on a strict definition of the intervention is important for a standardized delivery but, until recently, there was no consensus on the core attributes ... -
Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects
( Springer New York LLC , 2018 , Article Review)Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors ... -
Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis.
( Elsevier , 2019 , Article)T2DM reach epidemic levels in the Arab countries. In this study, we aimed to perform a systematic review and meta-analysis to underline the susceptibility genetic profile of Arab patients with T2DM that result from SNPs. ... -
IDF Diabetes Atlas: The prevalence of pre-existing diabetes in pregnancy – A systematic reviewand meta-analysis of studies published during 2010–2020
( Elsevier , 2021 , Article)ObjectivesTo estimate the prevalence of pre-existing diabetes in pregnancy from studies published during 2010–2020. MethodsWe searched PubMed, CINAHL, Scopus and other sources for relevant data sources. The prevalence of ... -
Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery.
( BMC , 2020 , Article)Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. In this study, metabolic profiling of blood samples collected ... -
Predictive Power of Body Visceral Adiposity Index, Body Adiposity Index and Body Mass Index for Type 2 Diabetes in Qatari Population
( Qatar University Press , 2020 , Poster)Background: The prevalence of type 2 diabetes (T2D) has increased recently in Qatar. Body mass index (BMI) is a predictor of T2D in many populations. However, BMI is based on height and weight measurements and not on body ... -
Primary vs Revisional Gastric Bypass for Weight Loss and Improvements in Comorbidities: Comparisons at Mid-term Follow-up
( Springer , 2019 , Article)Background: Revisional gastric bypass (R-RYGB) surgery is utilized for the management of inadequate weight loss or weight regain observed after some cases of bariatric surgeries. Data on the mid-term effectiveness of primary ... -
Relationship between material needs security and clinical outcomes in adults with type 2 diabetes in Lebanon
( Elsevier , 2022 , Article)BackgroundDespite their documented significance in type 2 diabetes (T2DM) management, social determinants of health (SDOHs) including material needs security are poorly studied in the Middle East and North Africa (MENA) ... -
Relationship between social determinants of health and quality of life in low income adults with diabetes in Lebanon
( Taylor and Francis Ltd. , 2023 , Article)Background & objective: Global rates of type 2 diabetes (T2DM) are increasing, with the Middle East and North Africa (MENA) region having the second highest prevalence in the world. Populations from the MENA region, including ... -
Results from the first culturally tailored, multidisciplinary diabetes education in Lebanese adults with type 2 diabetes: effects on self-care and metabolic outcomes
( BMC , 2022 , Article)Objective: Diabetes self-management education (DSME) is an essential component of lifestyle management needed for diabetes care. This pilot-study tested the effect of culturally-tailored education targeting diabetes selfcare ... -
Risk prediction models for incident type 2 diabetes in Chinese people with intermediate hyperglycemia: a systematic literature review and external validation study
( BMC , 2022 , Article)BACKGROUND: People with intermediate hyperglycemia (IH), including impaired fasting glucose and/or impaired glucose tolerance, are at higher risk of developing type 2 diabetes (T2D) than those with normoglycemia. We aimed ... -
Short-term improvements in diet quality in people newly diagnosed with type 2 diabetes are associated with smoking status, physical activity and body mass index: the 3D case series study.
( Springer Nature , 2020 , Article)Dietary intake impacts glycaemic control through its effect on weight and glucose-insulin homeostasis. Early glycaemic control is associated with improved outcomes and reduced mortality for people with type 2 diabetes ... -
Signal transducer and activator of transcription 3 (Stat3) suppresses stat1/interferon signaling pathway and inflammation in senescent preadipocytes
( MDPI , 2021 , Article)© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT ... -
Type 2 diabetes mellitus in pregnancy: The impact of maternal weight and early glycaemic control on outcomes.
( Elsevier , 2018 , Article)To study the pregnancy outcomes in women with type 2 diabetes mellitus (T2DM) and to relate these to maternal risk factors. We conducted a retrospective study of 419 women with T2DM (index group)- who attended our diabetes ... -
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
( Elsevier , 2023 , Article)In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type 2 diabetes ... -
Unifying the diagnosis of gestational diabetes mellitus: Introducing the NPRP criteria
( Elsevier , 2021 , Article)AimsDisagreement about the appropriate criteria for the diagnosis of gestational diabetes mellitus (GDM) persists. This study examines an alternative approach which combines information from all time-points on the glucose ... -
Visceral adiposity index is a better predictor of type 2 diabetes than body mass index in Qatari population
( Lippincott Williams and Wilkins , 2020 , Article)The prevalence of type 2 diabetes (T2D) has increased recently in Qatar. Body mass index (BMI) is a predictor of T2D in many populations. However, BMI is based on height and weight measurements and not on body adiposity. ... -
Worsening baroreflex sensitivity on progression to type 2 diabetes: Localized vs. systemic inflammation and role of antidiabetic therapy
( American Physiological Society , 2020 , Article)Cardiac autonomic neuropathy (CAN) is an early cardiovascular manifestation of type 2 diabetes (T2D) that constitutes an independent risk factor for cardiovascular mortality and morbidity. Nevertheless, its underlying ...