Browsing by Subject "Whole exome sequencing"

Now showing items 1-3 of 3

    • The Arab genome: Health and wealth 

      Zayed, Hatem ( Elsevier B.V. , 2016 , Article)
      The 22 Arab nations have a unique genetic structure, which reflects both conserved and diverse gene pools due to the prevalent endogamous and consanguineous marriage culture and the long history of admixture among different ...

    • Different molecular pathways are disrupted in Pyoderma gangrenosum patients and are associated with the severity of the disease. 

      Moura, Ronald Rodrigues; Brandão, Lucas; Moltrasio, Chiara; Agrelli, Almerinda; Tricarico, Paola Maura; ... more authors ( Nature Research , 2023 , Article)
      Pyoderma gangrenosum (PG) is a rare inflammatory skin disease classified within the spectrum of neutrophilic dermatoses. The pathophysiology of PG is yet incompletely understood but a prominent role of genetics facilitating ...

    • What is the right sequencing approach? Solo VS extended family analysis in consanguineous populations. 

      Alfares, Ahmed; Alsubaie, Lamia; Aloraini, Taghrid; Alaskar, Aljoharah; Althagafi, Azza; ... more authors ( Springer Nature , 2020 , Article)
      Testing strategies is crucial for genetics clinics and testing laboratories. In this study, we tried to compare the hit rate between solo and trio and trio plus testing and between trio and sibship testing. Finally, we ...