Browsing Master in Pharmacy by Publication Date
Now showing items 41-52 of 52
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DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONE ANALOGS AS POTENTIAL THERAPEUTIC AGENTS FOR CASTRATION RESISTANT PROSTATE CANCER
(2021 , Master Thesis)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
IMPACT OF SGLT2 INHIBITORS ON CKD PROGRESSION IN DIABETIC PATIENTS IN QATAR A RETROSPECTIVE COHORT STUDY
(2023 , Master Thesis)Background: The risk of end-stage renal disease rises is based on the estimated glomerular filtration rate (eGFR) reduction. Even though multiple large-scale clinical trials have demonstrated the preventive benefits of ... -
HYPERTENSION MANAGEMENT AND PRESCRIBING PRACTICES IN PRIMARY HEALTHCARE SETTINGS IN QATAR: A MULTI-METHODS
(2023 , Master Thesis)Background: The use of antihypertensive medications controls blood pressure (BP) and reduces the incidence of complications. This study explored the prescribing patterns and trends of antihypertensive medications utilization, ... -
EXPLORATION OF THE APPLICATION OF PHARMACOGENETICS IN THE MANAGEMENT OF DEPRESSION
(2023 , Master Thesis)Genetic factors have been reported as playing an important role in the treatment efficacy of antidepressants (ADs). Studies report up to 55 % of patients experience AD treatment failure. The aim of this research was to ... -
Anticancer Activity of Neosetophomone-B, a Fungal Secondary Metabolite, Against Hematological Malignancies
(2023 , Dissertation)Anticancer Activity of Neosetophomone-B, a Fungal Secondary Metabolite, Against Hematological Malignancies downregulation, and p21 and p27 upregulation were observed in NSP-B-treated leukemia, lymphoma, and myeloma cells. ... -
Trends and Appropriateness of Sodium-glucose Co-transporter 2 Inhibitors Use in Qatar
(2023 , Master Thesis)Background: Sodium glucose co-transporter 2 inhibitors (SGLT2is) are the most recently approved class of oral antidiabetic drugs (ADDs). The objective of this study was to explore the trends in the use of SGLT2is compared ... -
DRUG SURVIVAL OF DIFFERENT BIOLOGICS IN PSORIATIC PATIENTS - EVIDENCE SYNTHESIS AND HISTORICAL COHORT STUDY
(2023 , Master Thesis)Biologic therapies have revolutionized the treatment of psoriasis, providing high levels of efficacy and safety. However, the choice of the appropriate therapy for each patient remains a challenge. The primary objective ... -
Ethanol-Based Proliposomes Incorporating Dexamethasone for The Treatment of COVID-19 Acute Respiratory Distress Syndrome (ARDS) Using Medical Nebulizers
(2023 , Master Thesis)Background/Objective: Systemic dexamethasone has demonstrated mortality reduction in COVID-19-related acute respiratory distress syndrome (ARDS). The aim of this study is to use ethanol-based proliposome technology to ... -
Development of A Novel Liposomal Formulation of a Pyridine Chalcone Analogue for HER-2 Positive Breast Cancer
(2024 , Master Thesis)Breast cancer is the most prevalent cancer in women and the fifth leading cause of death due to cancer worldwide. Human epidermal growth factor receptor-2 (HER-2) is an oncoprotein that is overexpressed in 25-30% of breast ... -
Developing Pharmacist-Led Anticoagulation Clinics in Primary Care Settings: A Multi-Phase Mixed-Methods Study
(2024 , Master Thesis)Background: Primary care is an integral part of the healthcare system. Patients have better accessibility and continuity of care. However, studies have reported low-quality warfarin management in these settings. Pharmacist-led ... -
Nano Liposomal Formulation for A Novel Chalcone Compound as A Potential Anticancer Delivery System for Triple-Negative Breast Cancer
(2024 , Master Thesis)Triple negative breast cancer is the most aggressive type of breast malignancy accounting for 15-20% of all breast cancer cases. Treatment of TNBC remains limited, with a high risk of relapse and metastasis to other organs. ... -
The Cytotoxicity Of “Al-Siddir” Tree “Ziziphus Spina Christi” Methanolic Leaves Extract on Her-2 Positive Breast Cancer
(2024 , Master Thesis)HER-2 positive is a subtype of breast cancer that acquires poor prognosis and low survival rates. Targeted therapy is one of the main approaches that are used for the treatment of HER-2-positive breast cancer. However, it ...