Browsing Medicine Research by Title
Now showing items 1205-1224 of 1321
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The pleiotropic effects of antithrombotic drugs in the metabolic-cardiovascular-neurodegenerative disease continuum: Impact beyond reduced clotting
( Portland Press Ltd , 2021 , Article Review)Antithrombotic drugs are widely used for primary and secondary prevention, as well as treatment of many cardiovascular disorders. Over the past few decades, major advances in the pharmacology of these agents have been made ... -
The power of phytochemicals combination in cancer chemoprevention
( Ivyspring International Publisher , 2020 , Article Review)Conventional therapies for cancer treatment have posed many challenges, including toxicity, multidrug resistance and economic expenses. In contrast, complementary alternative medicine (CAM), employing phytochemicals have ... -
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis of 12 011 447 individuals
( Qatar University Press , 2021 , Poster)Research purpose: The research aims to estimate the prevalence of detectable SARS-CoV-2 antibodies, T and B memory cells after recovery, to determine the prevalence of SARS-CoV-2 reinfection, and to investigate the protective ... -
The psychological impact of the Turkey-Syria earthquake on children: addressing the need for ongoing mental health support and global humanitarian response
( Taylor and Francis Ltd. , 2023 , Other)This letter aims to explore the potential impact of the Turkey-Syria earthquake on the psychological well-being of the affected children and adolescents. It emphasises the crucial importance of prompt identification and ... -
The purification and identification of human blood serum proteins with affinity to the antitumor active RL2 lactaptin using magnetic microparticles
( John Wiley and Sons Ltd , 2019 , Article)The cytopoxic effect of RL2 lactaptin (the recombinant analog of proteolytic fragment of human kappa‐casein) toward tumor cells in vitro and in vivo presents it as a novel promising antitumor drug. The binding of any drug ... -
The risk of severe COVID-19 and mortality from COVID-19 in people living with HIV compared to individuals without HIV - a systematic review and meta-analysis of 1 268 676 individuals.
( Qatar University Press , 2021 , Poster)Research Purpose: Findings from existing studies have shown conflicting evidence concerning the risk of severe COVID-19 and death from COVID-19 in people living with HIV (PLHIV) compared to people without HIV. The aim of ... -
The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation
( Portland Press Ltd , 2017 , Article Review)At mammalian fertilisation, the fundamental stimulus that triggers oocyte (egg) activation and initiation of early embryonic development is an acute rise of the intracellular-free calcium (Ca2+) concentration inside the ... -
The role of anti-Mullerian hormone and other correlates in patients with polycystic ovary syndrome
( Taylor and Francis Ltd. , 2023 , Article)Background Anti-Müllerian hormone (AMH) has recently emerged as a promising biomarker for the detection of polycystic ovarian morphology. In polycystic ovary syndrome (PCOS), an elevated level of AMH has been suggested ... -
The role of antibiotic resistance mobile genetic element MCR-1 in enhancing bacterial survival in macrophages
( Hamad bin Khalifa University Press (HBKU Press) , 2022 , Article)Background: Antimicrobial resistance (AMR) determinants such as mobile colistin resistance (MCR-1) that encodes colistin resistance are increasingly spreading in healthcare-associated and community-acquired infections. 1 ... -
The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study
( Karolinum - Nakladatelstvi Univerzity Karlovy , 2023 , Article)The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical ... -
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
( Frontiers Media S.A. , 2021 , Article)Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. It ... -
The role of glycogen synthase kinase 3 (GSK3) in cancer with emphasis on ovarian cancer development and progression: A comprehensive review
( Association of Basic Medical Sciences of FBIH , 2021 , Article Review)Glycogen synthase kinase 3 (GSK3) is a monomeric serine-threonine kinase discovered in 1980 in a rat skeletal muscle. It has been involved in various cellular processes including embryogenesis, immune response, inflammation, ... -
The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
( MDPI AG , 2019 , Article Review)Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ... -
The role of Rezum in the management of refractory urinary retention due to benign prostate hyperplasia: A literature review
( Taylor and Francis Ltd. , 2023 , Article)Background: Benign prostatic hyperplasia is the most common cause of urinary retention in men (BPH). The gold standard surgical treatment is transurethral resection of the prostate (TURP). However, due to the morbidity and ... -
The unseen battle: A global call to safeguard the mental well-being of Palestinian children
( Elsevier , 2024 , Other)The long-standing and complex Israeli-Palestinian conflict has led to the widespread displacement of Palestinians and resulted in ongoing challenges for the Palestinian population (Feliciana, 2011). It has had a lasting ... -
Theranostic molecular profiling of pleomorphic ductal carcinoma of the breast.
( Wiley , 2019 , Other)Pleomorphic ductal carcinoma (PDC) is a very rare subtype of invasive ductal carcinoma of no‐special type (NST), characterized by the presence of highly atypical/bizarre (>6‐fold variation in nuclear size) and multinucleated ... -
The therapeutic effects of adipose-derived mesenchymal stem cells on obesity and its associated diseases in diet-induced obese mice
( Nature Research , 2021 , Article)Obesity is a global public health concern associated with increased risk of several comorbidities. Due to the limited effectiveness of current therapies, new treatment strategies are needed. Our aim was to examine the ... -
Therapeutic effects of statins on osteoarthritis: A review
( Wiley , 2022 , Article Review)Osteoarthritis (OA) is a progressive joint disease. The etiology of OA is considered to be multifactorial. Currently, there is no definitive treatment for OA, and the existing treatments are not very effective. ... -
Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
( Elsevier , 2022 , Article)Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ... -
Therapeutic potential of resveratrol in covid-19-associated hemostatic disorders
( MDPI , 2021 , Article)Coagulation disorders, endotheliopathy and inflammation are the most common hallmarks in SARS-CoV-2 infection, largely determining COVID-19's outcome and severity. Dysfunctions of endothelial cells and platelets are tightly ...