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Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
(
Elsevier
, 2022 , Article)
Human exposure to bisphenol A (BPA) is mainly due to migration from plastic packaging into food and beverages. Studies reported BPA endocrine disruptions through interactions with different nuclear receptors, including the ...
Effect of statins on abdominal aortic aneurysm
(
Elsevier
, 2022 , Article Review)
Abdominal aortic aneurysm (AAA) is a prevalent condition which causes progressive growth and rupture of aortic wall with a high death rate. Several studies have found that treatment with statins may decrease the progress ...
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
(
Elsevier
, 2021 , Article)
Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. Owing to ...
Nano-targeting vascular remodeling in cancer: Recent developments and future directions
(
Elsevier
, 2022 , Article Review)
Tumor growth and progression are strictly dependent on the adequate blood supply of oxygen and nutrients. The formation of new blood vessels and vascular networks is essential to ensure this demand. Blood vessels also ...
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
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Universita Cattolica del Sacro Cuore
, 2022 , Article)
Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ...
Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris
(
Frontiers Media
, 2021 , Article)
Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, ...
The Effects of Statin Treatment on Serum Ferritin Levels: A Systematic Review and Meta-Analysis
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2022 , Article)
Background: Statins are the most widely used drugs for decreasing elevated serum LDL-cholesterol (LDL-C) and thus for the prevention of atherosclerotic cardiovascular disease (ASCVD), but they have also some pleiotropic ...
Editorial: Methods and application in cardiovascular and smooth muscle pharmacology: 2021
(
Frontiers Media S.A.
, 2022 , Other)
Despite significant advances in basic, translational, and clinical research tackling heart disease, cardiovascular pathologies remain among the leading causes of mortality and morbidity worldwide, being responsible for ...
Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Cannabinoid receptors, which are widely distributed in the body, have been considered as possible pharmacological targets for the management of several tumors. Cannabinoid type 2 receptors (CB2Rs) belong to the G protein-coupled ...
Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
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Frontiers Media S.A.
, 2021 , Article)
A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it contributes to energy homeostasis and provides insulation for internal organs. Adipocytes were previously thought to be a passive ...