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Role of HMGB1 and its associated signaling pathways in human malignancies
(
Elsevier
, 2023 , Article)
The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ...
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
(
Elsevier
, 2024 , Article)
In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ...
Cultural Competence among Healthcare Professional Educators: A Mixed-Methods Study
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
As cultural diversity gains global prominence, healthcare professional educators (HPEs) are expected to exhibit a high level of cultural competence in education. Responding to this necessity requires the establishment of ...
Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance
(
Elsevier
, 2024 , Article)
Gynecological malignancies pose a severe threat to female lives. Ovarian cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. Several studies have ...
Portrayal of Autism Spectrum disorder and its treatments in Qatar's leading newspapers: A content analysis study
(
Elsevier
, 2024 , Article)
BackgroundThe public cultivates thoughts, perceptions, and beliefs through media. Research has revealed that the media has a significant contribution to the publics’ negative perceptions and stigma surrounding Autism ...
Efficacy and safety of selinexor for patients with relapsed and refractory multiple myeloma: A meta-analysis
(
Elsevier
, 2024 , Article)
PurposeSelinexor is a first-in-class, oral selective-inhibitor-of-nuclear-export, granted accelerated approval by FDA (2019) for relapsed and refractory multiple myeloma (RRMM). We sought to quantitatively summarize the ...
Pharmacy Students’ Perception of the Content and Delivery of Drug Information Training: A Mixed-Methods Study
(
Elsevier
, 2024 , Article)
Objective: To explore the pharmacy students’ perception of the content and pedagogical strategies used for the delivery of drug information (DI) training. Methods: An explanatory sequential mixed-methods study was conducted ...
Parents’ behaviour toward antibiotic self-medication in children and incidence of resistance: a cross-sectional study from Punjab, Pakistan
(
Wydawnictwo Continuo
, 2024 , Article)
Background. Antibiotic resistance is mostly brought about through antibiotic self-medication, which is a common issue in impoverished countries. The most at-risk group is children, while there is no protection evidence ...
A cross-sectional survey among parents to report challenges and barriers in the administration of drugs to children
(
Taylor & Francis
, 2022 , Article)
Background: Lack of knowledge among parents can result in inappropriate administration practices. After analyzing different studies among children, there was no data on challenges and barriers in the administration of ...
The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar
(
Taylor and Francis Ltd.
, 2024 , Article)
Objective: To estimate the economic impact of the developed antimicrobial stewardship program (ASP) versus the preliminary ASP use, in the adults' general medicine settings in Qatar. Methods: Patient records were retrospectively ...