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Now showing items 11-20 of 21
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Epstein-Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis
(
Frontiers Media S.A.
, 2018 , Article Review)
The Epstein-Barr virus (EBV) is the first herpesvirus identified to be associated with human cancers known to infect the majority of the world population. EBV-associated malignancies are associated with a latent form of ...
Laboratory challenges in the diagnosis of hepatitis E virus.
(
Microbiology Society
, 2018 , Article Review)
Hepatitis E virus (HEV) is an RNA virus that is an important cause of both acute and chronic hepatitis worldwide. To date, there are eight HEV genotypes that can infect mammals. HEV-1 and HEV-2 infect exclusively humans, ...
Estrogen in vascular smooth muscle cells: A friend or a foe?
(
Elsevier Inc.
, 2018 , Article Review)
Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. The effect of estrogen on these diseases has been assessed in in vitro and in vivo models, as well as in observational studies. Collectively, ...
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
(
Frontiers Media
, 2018 , Article Review)
Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ...
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
(
Frontiers Medi
, 2018 , Article Review)
The Epstein–Barr virus (EBV) is a DNA lymphotropic herpesvirus and the causative agent
of infectious mononucleosis. EBV is highly prevalent since it affects more than 90% of
individuals worldwide and has been linked to ...
Prevalence of nephropathy in type 1 diabetes in the Arab world: A systematic review and meta-analysis
(
John Wiley and Sons Ltd
, 2018 , Article Review)
The aim of this study was to conduct a systematic review and meta-analysis and determine the prevalence of diabetic nephropathy (DN) among Arab patients with T1D. A systematic literature search was conducted using 4 different ...
Meta-analysis of the incidence of lead dislodgement with conventional and leadless pacemaker systems
(
Blackwell Publishing Inc.
, 2018 , Article Review)
Introduction
Leadless cardiac pacemaker (LCP) implantation using a transcatheter was recently developed to avoid pocket- and lead-related complications. Although a LCP has an active fixation mechanism using tines or a ...
A potential link between oxidative stress and endothelial-to-mesenchymal transition in systemic sclerosis
(
Frontiers Media S.A.
, 2018 , Article Review)
Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of genetic and environmental risk factors, is characterized by progressive fibrosis and microvasculature damage in the skin, lungs, heart, ...
Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: Potentials and limitations
(
Elsevier
, 2014 , Article Review)
Avian pathogenic Escherichia coli (APEC) is one of the most economically devastating pathogens affecting the poultry industry. This group of extra-intestinal E. coli causes a variety of clinical conditions including ...