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Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
(
Portland Press Ltd
, 2024 , Article)
Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). CBS is an essential pyridoxal 50-phosphate (PLP)-dependent enzyme in the transsulfuration ...
Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetes
(
Royal Society of Chemistry
, 2013 , Article)
Type 2 diabetes (T2DM) is a multi-factorial disease with a complex pathogenic mechanism; however a complete understanding of precise biochemical alterations accompanying the onset and progression of T2DM is lacking. Using ...
Total and high molecular weight adiponectin in patients with coronary artery disease
(
Wolters Kluwer Health
, 2009 , Article)
BACKGROUND: Serum adiponectin inversely correlates with the extent of coronary artery disease (CAD). OBJECTIVES: To investigate the clinical significance of measuring high molecular weight (HMW) adiponectin in addition to ...
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
(
Wolters Kluwer Health
, 2015 , Article)
Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ...
Hypoadiponectinemia in obese and diabetic subjects in the State of Qatar
(
Karger
, 2008 , Article)
Background: Obesity is commonly associated with insulin resistance (IR), and is a common cause of type 2 diabetes. Adiponectin is an adipose tissue protein that enhances insulin sensitivity and has anti-atherogenic properties. ...
The prevalence of vitamin d deficiency among female college students at Qatar University
(
Saudi Arabian Armed Forces Hospital
, 2011 , Article)
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Advances in vaccination against avian pathogenic Escherichia coli respiratory disease: Potentials and limitations
(
Elsevier
, 2014 , Article Review)
Avian pathogenic Escherichia coli (APEC) is one of the most economically devastating pathogens affecting the poultry industry. This group of extra-intestinal E. coli causes a variety of clinical conditions including ...
Social resources and Arab women's perinatal mental health: A systematic review
(
Elsevier B.V.
, 2018 , Article)
Background
Women’s mental health in the perinatal period is understudied worldwide and in Arab countries especially.
Aim
This systematic review explores evidence of the association between women’s social resources for ...
Non-communicable diseases in the Arab world
(
Elsevier Ltd
, 2014 , Article Review)
According to the results of the Global Burden of Disease Study 2010, the burden of non-communicable diseases (cardiovascular disease, cancer, chronic lung diseases, and diabetes) in the Arab world has increased, with ...
Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct stones: a multicentre, single-blinded, randomised controlled trial
(
Elsevier Ltd
, 2019 , Article)
Background
Endoscopic sphincterotomy is the established treatment for common bile duct stones. Balloon dilation offers an alternative. Prolonged dilation (300 s) with a 10 mm diameter balloon decreases the occurrence of ...