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Use of Germ-Free Animal Models in Microbiota-Related Research
(
The Korean Society for Microbiology and Biotechnology
, 2015 , Article)
The large intestine is a home for trillions of microbiota, which confer many benefits on the host, including production of vitamins, absorption of nutrients, pathogen displacement, and development of the immune system. For ...
Seroprevalence of hepatitis E virus among blood donors in Qatar (2013-2016)
(
Wiley
, 2017 , Article)
BACKGROUND
Hepatitis E virus (HEV) is an RNA virus transmitted mainly through zoonotic transmission or fecal–oral route. More than 80% of Qatar's population are expatriates, including many coming from hyperendemic ...
Krabbe Disease in the Arab World
(
IOS Press
, 2015 , Article)
The autosomal recessive inherited Krabbe disease (KD) is a devastating pediatric lysosomal storage disorder affecting white matter of the brain. It is caused by mutations in the gene coding for the lysosomal enzyme ...
Initial psychometric testing and validation of the Patient Participation in Pressure Injury Prevention scale
(
Wiley
, 2017 , Article)
AIMS:
The aim of this study was to develop the Patient Participation in Pressure Injury Prevention (PPPIP) scale and undertake initial testing of some of its psychometric properties.
BACKGROUND:
Clinical practice ...
Pharmacotherapy of Persons with Dementia in Long-Term Care in Australia: A Descriptive Audit of Central Nervous System Medications
(
Bentham Science Publishers
, 2017 , Article)
BACKGROUND:
Neuropsychiatric symptoms of dementia are often treated through the prescription of one or more psychotropic medications. However, limited efficacy and potential harmful side-effects has resulted in efforts ...
Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
(
Elsevier
, 2017 , Article)
Green tea consumption has been shown to possess cancer chemopreventive activity. Polyphenol E (PE) is a widely used standardized green tea extract formulation. This study was designed to investigate the impact of PE on ...
Nose-to-brain delivery of BACE1 siRNA loaded in solid lipid nanoparticles for Alzheimer’s therapy
(
Elsevier
, 2017 , Article)
Abstract We designed a delivery system to obtain an efficient and optimal nose-to-brain transport of BACE1 siRNA, potentially useful in the treatment of Alzheimer's disease. We selected a cell-penetrating peptide, the short ...
Bioavailability and hypolipidemic effects of peanut skin polyphenols
(
Mary Ann Liebert, Inc.
, 2015 , Article)
Peanut skin is a rich source of polyphenols, such as proanthocyanidins. Peanut skin proanthocyanidins mainly
consist of a subgroup called procyanidins. Peanut-based procyanidins contain oligomers of both type A and type ...
Clinical Exome Sequencing unravels new disease-causing mutations in the myeloproliferative neoplasms: A pilot study in patients from the state of Qatar.
(
Elsevier
, 2018 , Article)
Clinical Exome Sequencing (CES) has increasingly become a popular diagnostic tool in patients suffering from genetic disorders that are clinically and genetically complicated. Myeloproliferative Neoplasms (MPNs) is an ...
Glycemic index of selected carbohydrate-based foods consumed in Qatar
(
Taylor & Francis
, 2010 , Article)
This study determined the glycemic index (GI) of selected carbohydrate-rich foods consumed in
Qatar. Recruited volunteers (n = 19) consumed two reference foods, glucose and white bread,
and 10 test foods. The foods tested ...