Browsing by Author "Al-Saad K."
Now showing items 1-10 of 10
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A simple model for cell type recognition using 2D-correlation analysis of FTIR images from breast cancer tissue
Ali M.H.; Rakib F.; Al-Saad K.; Al-Saady R.; Lyng F.M.; Goormaghtigh E.... more authors ... less authors ( Elsevier B.V. , 2018 , Article)Breast cancer is the second most common cancer after lung cancer. So far, in clinical practice, most cancer parameters originating from histopathology rely on the visualization by a pathologist of microscopic structures ... -
An Innovative Platform Merging Elemental Analysis and Ftir Imaging for Breast Tissue Analysis
Ali M.H.M.; Rakib F.; Al-Saad K.; Al-Saady R.; Goormaghtigh E. ( Nature Publishing Group , 2019 , Article)Histopathology and immunohistology remain the gold standard for breast cancer diagnostic. Yet, these approaches do not usually provide a sufficiently detailed characterization of the pathology. The purpose of this work is ... -
Application of fractional factorial design for green synthesis of cyano-modified silica nanoparticles: Chemometrics and multifarious response optimization
Elazazy M.S.; Issa A.A.; Al-Mashreky M.; Al-Sulaiti M.; Al-Saad K. ( Elsevier B.V. , 2018 , Article)Cyano-functionalized spherical silica nanoparticles (SNPs) were synthesized via St?ber method. A 2 k-p IV fractional factorial design (2k-p IV-FFD) was used to smartly prepare monodispersed evenly distributed SNPs. Six ... -
Application of FTIR and LA-ICPMS spectroscopies as a possible approach for biochemical analyses of different rat brain regions
Ali M.H.M.; Rakib F.; Nischwitz V.; Ullah E.; Mall R.; Shraim A.M.; Ahmad M.I.; Ghouri Z.K.; McNaughton D.; Kuppers S.; Ahmed T.; Al-Saad K.... more authors ... less authors ( MDPI AG , 2018 , Article)Fourier Transform Infrared Spectroscopy (FTIR) is a non-destructive analytical technique that has been employed in this research to characterize the biochemical make-up of various rat brain regions. The sensorimotor cortex, ... -
Discrimination of breast cancer from benign tumours using Raman spectroscopy
Lyng F.M.; Traynor D.; Nguyen T.N.Q.; Meade A.D.; Rakib F.; Al-Saady R.; Goormaghtigh E.; Al-Saad K.; Ali M.H.... more authors ... less authors ( Public Library of Science , 2019 , Article)Breast cancer is the most common cancer among women worldwide, with an estimated 1.7 million cases and 522,000 deaths in 2012. Breast cancer is diagnosed by histopathological examination of breast biopsy material but this ... -
Fourier-transform infrared imaging spectroscopy and laser ablation -ICPMS new vistas for biochemical analyses of ischemic stroke in rat brain
Ali M.H.M.; Rakib F.; Abdelalim E.M.; Limbeck A.; Mall R.; Ullah E.; Mesaeli N.; McNaughton D.; Ahmed T.; Al-Saad K.... more authors ... less authors ( Frontiers Media S.A. , 2018 , Article)Objective: Stroke is the main cause of adult disability in the world, leaving more than half of the patients dependent on daily assistance. Understanding the post-stroke biochemical and molecular changes are critical for ... -
Investigation of the effect of PD-L1 blockade on triple negative breast cancer cells using fourier transform infrared spectroscopy
Ali M.H.M.; Toor S.M.; Rakib F.; Mall R.; Ullah E.; Mroue K.; Kolatkar P.R.; Al-Saad K.; Elkord E.... more authors ... less authors ( MDPI AG , 2019 , Article)Interactions between programmed death-1 (PD-1) with its ligand PD-L1 on tumor cells can antagonize T cell responses. Inhibiting these interactions using immune checkpoint inhibitors has shown promise in cancer immunotherapy. ... -
Pomegranate peels as versatile adsorbents for water purification: Application of box–behnken design as a methodological optimization approach
El-Azazy M.; Kalla R.N.; Issa A.A.; Al-Sulaiti M.; El-Shafie A.S.; Shomar B.; Al-Saad K.... more authors ... less authors ( John Wiley and Sons Inc. , 2019 , Article)Pomegranate peels (PGP) were tested as a green adsorbent for the removal of Ni(II) from contaminated water samples. Both raw (RPG), and char/burnt peels (BPG) were tested. A multivariate analysis approach, Box–Behnken (BB) ... -
Recycling of Date Pits Into a Green Adsorbent for Removal of Heavy Metals: A Fractional Factorial Design-Based Approach
Al-Saad K.; El-Azazy M.; Issa A.A.; Al-Yafie A.; El-Shafie A.S.; Al-Sulaiti M.; Shomar B.... more authors ... less authors ( Frontiers Media S.A. , 2019 , Article)Date pits (DPs) have been recycled into a low-cost adsorbent for removing of selected heavy metals (HMs) from artificially contaminated aqueous solutions. Adsorption of targeted HMs, both by raw date pits (RDP) and burnt ... -
Smart Synthesis of Trimethyl Ethoxysilane (TMS) Functionalized Core–Shell Magnetic Nanosorbents Fe3O4@SiO2: Process Optimization and Application for Extraction of Pesticides
Al-Saad K.; Issa A.A.; Idoudi S.; Shomar B.; Al-Ghouti M.A.; Al-Hashimi N.; El-Azazy M.... more authors ... less authors ( MDPI AG , 2020 , Article)In the current study, a smart approach for synthesizing trimethyl ethoxysilane–decorated magnetic-core silica-nanoparticles (TMS-mcSNPs) and its effectiveness as nanosorbents have been exploited. While the magnetite core ...