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Beta-blocker therapy in heart failure with preserved ejection fraction (B-HFpEF): A systematic review and meta-analysis
(
Elsevier Inc.
, 2024 , Article)
Introduction: While beta-blockers are considered the cornerstone of treatment for heart failure with reduced ejection fraction, the same may not apply to patients with heart failure with preserved ejection fraction (HFpEF). ...
Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): A randomised controlled trial protocol
(
BMJ Publishing Group
, 2024 , Article)
Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion ...
Food safety-related practices among residents aged 18–75 years during the COVID-19 pandemic: a cross-sectional study in Southwest China
(
BioMed Central Ltd
, 2024 , Article)
Background: Good food safety practices are essential to minimizing foodborne diseases. The present study explored the food safety-related practices of residents during the COVID-19 pandemic in Southwest China and identified ...
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
(
Elsevier B.V.
, 2024 , Article)
The unfolded protein response (UPR) detects increased misfolded proteins and activates protein refolding, protein degradation and inflammatory responses. UPR sensors in the endoplasmic reticulum, IRE1α and PERK, bind and ...
Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells
(
Taylor and Francis Ltd.
, 2024 , Article)
In this study, we investigated the effects of an ethanolic extract of Mangifera indica L. kernel on the viability and proliferation of human lung cancer cells. We utilized MTT and BrdU cell proliferation assays, morphological ...
Factors Affecting Healthcare Provider Referral to Heart Function Clinics: A Mixed-Methods Study
(
Wolters Kluwer Health
, 2024 , Article)
Background Heart failure (HF) care providers are gatekeepers for patients to appropriately access lifesaving HF clinics. Objective The aim of this study was to investigate referring providers' perceptions regarding referral ...
Spectral-based optimal output-feedback boundary control of a cracking catalytic reactor PDE model
(
Taylor and Francis Ltd.
, 2024 , Article)
This research paper focuses on the design of a boundary optimal controller with output feedback for a tubular catalytic cracking reactor. The process is represented by a set of non-linear parabolic partial differential ...
Prevalence of Blastocystis sp. and other gastrointestinal pathogens among diarrheic COVID-19 patients in Italy
(
Elsevier
, 2024 , Article)
BackgroundGastrointestinal pathogens (GPs) contribute significantly to the burden of illness worldwide with diarrhoea being the most common among gastrointestinal symptoms (GSs). In the COVID-19 disease, diarrhoea, could ...
Redefining Postpartum Depression Treatment: The Clinical Potential of Zuranolone
(
Elsevier
, 2024 , Other)
We write to bring to attention a pressing health concern: Postpartum Depression (PPD), which affects a significant 17% of mothers globally (Wang et al., 2021). This psychiatric condition manifests as intense mood swings, ...
Ether, sulfide and sulfone derivatives of cinnamaldehyde: Insights into synthesis, structural elucidation and solvatochromism
(
Elsevier B.V.
, 2024 , Article)
Symmetric ether, sulfide and sulfone derivatives based on Schiff base functionalized group (3a-c) were synthesized via classical condensation of 4,4′-diaminodiphenyl precursors (1a-c) and cinnamaldehyde (2) in methanol at ...