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Impact of Physical Exercise on Gut Microbiome, Inflammation, and the Pathobiology of Metabolic Disorders.
(
The Society for Biomedical
, 2019 , Article Review)
The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and energy homeostasis. ...
GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
(
PubMed Central
, 2020 , Article Review)
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Advancing Frontiers in Bone Bioprinting
(
Wiley-VCH Verlag
, 2019 , Article Review)
Three-dimensional (3D) bioprinting of cell-laden biomaterials is used to fabricate constructs that can mimic the structure of native tissues. The main techniques used for 3D bioprinting include microextrusion, inkjet, and ...
Targeting triple negative breast cancer heterogeneity with chalcones: a molecular insight.
(
Informa Healthcare
, 2019 , Article Review)
Triple negative breast cancers (TNBCs) are aggressive heterogeneous cancers with not yet determined conventional targeted medication. Therefore, identification of new alternatives or improved treatment options to combat ...
Architecture of Viral RNA Helicases; HCV Helicase as Antiviral Target
(2018 , Article Review)
Around 80% of known viruses comprise of RNA and its specific RNA helicases that are vital for most RNA metabolism
includingpre-mRNA splicing, translation,initiation, and ribosome biogenesis. The viral helicases are crucial ...
Advances in osteobiologic materials for bone substitutes.
(
John Wiley and Sons
, 2018 , Article Review)
A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ...
Translating advances in organ-on-a-chip technology for supporting organs
(
John Wiley and Sons Inc.
, 2019 , Article Review)
Organ‐on‐a‐chip platforms have recently seen tremendous progress. They have found potential applications in the study of physiology and pathology of tissues, drug toxicity, and development of tissue models for replacement ...
Novel CD44-downstream signaling pathways mediating breast tumor invasion
(
Ivyspring International Publisher
, 2018 , Article Review)
CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell
and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways,
including ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...