Browsing Biomedical Sciences by Author "Cheema, Amrita K."
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Erratum: ITRAQ-based Quantitative Protein Expression Profiling and MRM Verification of Markers in Type 2 Diabetes (Journal of Proteome Research (2012) 11 (5527-5537) DOI: 10.1021/pr300798z)
Kaur, Prabhjit; Rizk, Nasser M.; Ibrahim, Sereen; Younes, Noura; Uppal, Arushi; Dennis, Kevin; Karve, Tejaswita; Blakeslee, Kenneth; Kwagyan, John; Zirie, Mahmoud; Ressom, Habtom W.; Cheema, Amrita K.... more authors ... less authors ( American Chemical Society (ACS) , 2013 , Article)a Serum samples obtained from individual subjects were analyzed to determine the levels of glucose, Vitamin D among others (as described in methods). The value spreads within the group for each parameter are indicated as ... -
Integrated datasets of proteomic and metabolomic biomarkers to predict its impacts on comorbidities of type 2 diabetes mellitus
Cheema, Amrita K.; Kaur, Prabhjit; Fadel, Amina; Younes, Noura; Zirie, Mahmoud; Rizk, Nasser M.... more authors ... less authors ( Dove Medical Press , 2020 , Article)© 2020 Cheema et al. Objective: The objective of the current study is to accomplish a relative exploration of the biological roles of differentially dysregulated genes (DRGs) in type 2 diabetes mellitus (T2DM). The study ... -
iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes.
Uppal, , Arushi; Dennis, Kevin; Karve, ,Tejaswita; Blakeslee, , Kenneth; Kwagyan, John; Zirie, , Mahmoud; Younes, Noura; Ibrahim, Sereen; Kaur, , Prabhjit; Rizk, Nasser M; Cheema, Amrita K... more authors ... less authors ( American Chemical Society , 2012 , Article)The pathogenesis of Type 2 diabetes mellitus (T2DM) is complex owing to molecular heterogeneity in the afflicted population. Current diagnostic methods rely on blood glucose measurements, which are noninformative with ... -
Metabolomic biomarkers of pancreatic cancer: a meta-analysis study
Mehta, Khyati Y.; Wu, Hung-Jen; Menon, Smrithi S.; Fallah, Yassi; Zhong, Xiaogang; Rizk, Nasser; Unger, Keith; Mapstone, Mark; Fiandaca, Massimo S.; Federoff, Howard J.; Cheema, Amrita K.... more authors ... less authors ( Impact Journals , 2017 , Article)Pancreatic cancer (PC) is an aggressive disease with high mortality rates, however, there is no blood test for early detection and diagnosis of this disease. Several research groups have reported on metabolomics based ... -
Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetes
Kaur, Prabhjit; Rizk, Nasser; Ibrahim, Sereen; Luo, Yue; Younes, Noura; Perry, Brian; Dennis, Kevin; Zirie, Mahmoud; Luta, George; Cheema, Amrita K.... more authors ... less authors ( Royal Society of Chemistry , 2013 , Article)Type 2 diabetes (T2DM) is a multi-factorial disease with a complex pathogenic mechanism; however a complete understanding of precise biochemical alterations accompanying the onset and progression of T2DM is lacking. Using ...