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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte.
(
Wiley
, 2018 , Article)
In the central nervous system (CNS), oligodendrocytes are the glial element in charge of myelin formation. Obtaining an overall presence of oligodendrocyte precursor cells/oligodendrocytes (OPCs/OLs) in culture from different ...
Landscape of NAT2 polymorphisms among breast cancer.
(
Elsevier Masson
, 2016 , Article)
PURPOSE:
The prevalence of phenotypes of Arylamine N-acetyltransferase-2(NAT2) gene (i.e. fast, intermediate and slow acetylators) among ethnic groups, as well as the association studies regarding NAT2 polymorphisms and ...
Common and Rare Genetic Variants Associated With Alzheimer's Disease
(
WILEY PERIODICALS, INC.
, 2016 , Article)
Alzheimer's disease (AD) is one of the most devastating disorders. Despite the continuing increase of its incidence among aging populations, no effective cure has been developed mainly due to difficulties in early diagnosis ...
Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson's disease.
(
Wiley
, 2015 , Article)
Parkinson's disease (PD) is a neurological disorder characterized by the loss of midbrain dopaminergic (DA) neurons. Neural stem cells (NSCs) are multipotent stem cells that are capable of differentiating into different ...
Aspirin inhibits cancer stem cells properties and growth of glioblastoma multiforme through Rb1 pathway modulation.
(
Wiley
, 2019 , Article)
Several clinical studies indicated that the daily use of aspirin or acetylsalicylic acid reduces the cancer risk via cyclooxygenases (Cox-1 and Cox-2) inhibition. In addition, aspirin-induced Cox-dependent and -independent ...
Recent Perspective About the Amyloid Cascade Hypothesis and Stem Cell-Based Therapy in the Treatment of Alzheimer's Disease
(
Bentham Science
, 2016 , Book chapter)
Alzheimer's disease (AD) is a complex neurodegenerative condition that is
clinically characterized by impaired cognitive functions. The major morphologically
observed lesion of AD encompasses the accumulation of extracellular ...
Advances in osteobiologic materials for bone substitutes.
(
John Wiley and Sons
, 2018 , Article Review)
A significant challenge in the current orthopedics is the development of suitable osteobiologic materials that can replace the conventional allografts, autografts, and xenografts and thereby serve as implant materials as ...
Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
(
Wiley
, 2015 , Article)
In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs)
transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ...
Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes.
(
Elsevier
, 2019 , Article)
The chimeric antigen receptor Tcell (CAR-T cell) immunotherapy currently represents a hot research trend and it is expected to revolutionize the field of cancer therapy. Promising outcomes have been achieved using CAR-T ...
Pseudomonas aeruginosa: arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies.
(
Future Medicine
, 2015 , Article)
Antimicrobial resistance is one of the most serious public health issues facing humans since the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of antimicrobial agents are major factors ...