Browsing by Author "Georgakopoulos-Soares, Ilias"

Now showing items 1-3 of 3

    • Distinct genomic features across cytolytic subgroups in skin melanoma. 

      Roufas, Constantinos; Georgakopoulos-Soares, Ilias; Zaravinos, Apostolos ( Springer , 2021 , Article)
      Skin melanoma is a highly immunogenic cancer. The intratumoral immune cytolytic activity (CYT) reflects the ability of cytotoxic T and NK cells to eliminate cancer cells, and is associated with improved patient survival. ...

    • EMT Factors and Metabolic Pathways in Cancer. 

      Georgakopoulos-Soares, Ilias; Chartoumpekis, Dionysios V.; Kyriazopoulou, Venetsana; Apostolos, Zaravinos ( Frontiers Media , 2020 , Article)
      The epithelial-mesenchymal transition (EMT) represents a biological program during which epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is normally observed during organismal development, ...

    • Molecular correlates of immune cytolytic subgroups in colorectal cancer by integrated genomics analysis 

      Roufas, Constantinos; Georgakopoulos-Soares, Ilias; Zaravinos, Apostolos ( Oxford University Press , 2021 , Article)
      Although immune checkpoint inhibition (ICI) has shown promising results in metastatic dMMR/MSI-H colorectal cancer (CRC), the majority of pMMR/MSS patients do not respond to such therapies. To systematically evaluate the ...