Browsing by Author "Khalaf, Sarah"
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells.
Alhoshani, Ali; Alatawi, Fahad O; Al-Anazi, Fawaz E; Attafi, Ibraheem M; Zeidan, Asad; Agouni, Abdelali; El Gamal, Heba M; Shamoon, Licia S; Khalaf, Sarah; Korashy, Hesham M... more authors ... less authors ( Dove Medical Press , 2020 , Article)Venetoclax (VCX) is a selective BCL-2 inhibitor approved for the treatment of leukemia and lymphoma. However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic ... -
Metformin and HER2-positive breast cancer: Mechanisms and therapeutic implications
Bashraheel, Sara S.; Kheraldine, Hadeel; Khalaf, Sarah; Moustafa, Ala Eddin Al ( Elsevier , 2023 , Article)Due to the strong association between diabetes and cancer incidents, several anti-diabetic drugs, including metformin, have been examined for their anticancer activity. Metformin is a biguanide antihyperglycemic agent used ...