Browsing by Author "Balasundaram, Ambritha"
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Chapter Four Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach
N., Madhana Priya; Balasundaram, Ambritha; Sidharth Kumar, N.; Udhaya Kumar, S.; Thirumal Kumar, D.; Magesh, R.; Zayed, Hatem; George Priya Doss, C.... more authors ... less authors ( Elsevier , 2023 , Book chapter)Cyclin-dependent kinase 6 (CDK6) is an essential kinase in cell cycle progression, which is a viable target for inhibitors in various malignancies, including breast cancer. This study aimed to virtually screen efficient ... -
Integrative ontology and pathway-based approach identifies distinct molecular signatures in transcriptomes of esophageal squamous cell carcinoma
Udhaya Kumar, S.; Balasundaram, Ambritha; Anu Preethi, V.; Chatterjee, Sayoni; Kameshwari Gollakota, G.V.; Kashyap, Manoj Kumar; George Priya Doss, C.; Zayed, Hatem... more authors ... less authors ( Elsevier , 2022 , Book chapter)Esophageal squamous cell carcinoma (ESCC) remains a serious concern globally due to many factors that including late diagnosis, lack of an ideal biomarker for diagnosis and prognosis, and high rate of mortality. In this ... -
Whole-exome sequencing analysis of NSCLC reveals the pathogenic missense variants from cancer-associated genes
Kumar S, Udhaya; Balasundaram, Ambritha; Cathryn R, Hephzibah; Varghese, Rinku Polachirakkal; R, Siva; R, Gnanasambandan; Younes, Salma; Zayed, Hatem; Doss C, George Priya... more authors ... less authors ( Elsevier , 2022 , Article)Background: Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer. NSCLC accounts for 84% of all lung cancer cases. In recent years, advances in pathway understanding, methods for discovering novel ...