Browsing by Author "AlDhaheri, Yusra"
Now showing items 1-14 of 14
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Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Production
Al Dhaheri, Yusra; Attoub, Samir; Arafat, Kholoud; AbuQamar, Synan; Viallet, Jean; Saleh, Alaaeldin; Al Agha, Hala; Eid, Ali; Iratni, Rabah... more authors ... less authors ( Public Library of Science , 2013 , Article)Background: We have recently reported that Origanum majorana exhibits anticancer activity by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer cell line. Here, we extended our study by ... -
Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats
Hosseini, Azar; Safari, Mohammad Kazem; Rajabian, Arezoo; Boroumand-Noughabi, Samaneh; Eid, Ali H.; Al Dhaheri, Yusra; Gumpricht, Eric; Sahebkar, Amirhossein... more authors ... less authors ( Frontiers Media S.A. , 2022 , Article)Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum ... -
Chemical Analysis and Investigation of Biological Effects of Salvia officinalis Essential Oils at Three Phenological Stages
Assaggaf, Hamza M.; Naceiri Mrabti, Hanae; Rajab, Bodour S.; Attar, Ammar A.; Alyamani, Reema A.; Hamed, Munerah; El Omari, Nasreddine; El Menyiy, Naoual; Hazzoumi, Zakaria; Benali, Taoufiq; Al-Mijalli, Samiah Hamad; Zengin, Gokhan; AlDhaheri, Yusra; Eid, Ali H.; Bouyahya, Abdelhakim... more authors ... less authors ( MDPI , 2022 , Article)Salvia officinalis is a medicinal plant used to treat some diseases, including microbial infections and diabetes. Different studies showed the biological and pharmacological properties of this species. The aim of this study ... -
Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53
Al Dhaheri, Yusra; Eid, Ali; AbuQamar, Synan; Attoub, Samir; Khasawneh, Mohammad; Aiche, Ghenima; Hisaindee, Soleiman; Iratni, Rabah... more authors ... less authors ( Public Library of Science , 2013 , Article)Background: In the present study, we investigated the effect of Origanum majorana ethanolic extract on the survival of the highly proliferative and invasive triple-negative p53 mutant breast cancer cell line MDA-MB-231. ... -
Papaver Plants: Current Insights on Phytochemical and Nutritional Composition Along with Biotechnological Applications
Butnariu, Monica; Quispe, Cristina; Herrera-Bravo, Jesús; Pentea, Marius; Sarac, Ioan; Küşümler, Aylin Seylam; Özçelik, Beraat; Painuli, Sakshi; Semwal, Prabhakar; Imran, Muhammad; Gondal, Tanweer Aslam; Emamzadeh-Yazdi, Simin; Lapava, Natallia; Yousaf, Zubaida; Kumar, Manoj; Eid, Ali Hussein; Al-Dhaheri, Yusra; Suleria, Hafiz Ansar Rasul; Contreras, María del Mar; Sharifi-Rad, Javad; Cho, William C.... more authors ... less authors ( Hindawi , 2022 , Article)The genus Papaver is highly esteemed in the pharmacy industry, in the culinary field, and as ornamental plants. These plants are also valued in traditional medicine. Among all Papaver species, Papaver somniferum L. (opium ... -
Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
Hammoud, Safaa H.; AlZaim, Ibrahim; Al-Dhaheri, Yusra; Eid, Ali H.; El-Yazbi, Ahmed F. ( Frontiers Media S.A. , 2021 , Article)A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it contributes to energy homeostasis and provides insulation for internal organs. Adipocytes were previously thought to be a passive ... -
Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
Altabbal, Suhib; Athamnah, Khawla; Rahma, Aaesha; Wali, Adil Farooq; Eid, Ali H.; Iratni, Rabah; Al Dhaheri, Yusra... more authors ... less authors ( MDPI , 2023 , Article)Cancer is the second most life-threatening disease and has become a global health and economic problem worldwide. Due to the multifactorial nature of cancer, its pathophysiology is not completely understood so far, which ... -
Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation
El Hasasna, Hussain; Athamneh, Khawlah; Al Samri, Halima; Karuvantevida, Noushad; Al Dhaheri, Yusra; Hisaindee, Soleiman; Ramadan, Gaber; Al Tamimi, Nedaa; AbuQamar, Synan; Eid, Ali; Iratni, Rabah... more authors ... less authors ( Nature Publishing Group , 2015 , Article)Here, we investigated the anticancer effect of Rhus coriaria on three breast cancer cell lines. We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and ... -
Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways
El Hasasna, Hussain; Saleh, Alaaeldin; Al Samri, Halima; Athamneh, Khawlah; Attoub, Samir; Arafat, Kholoud; Benhalilou, Nehla; Alyan, Sofyan; Viallet, Jean; Al Dhaheri, Yusra; Eid, Ali; Iratni, Rabah... more authors ... less authors ( Nature Publishing Group , 2016 , Article)Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer cells. Here, we investigated the ... -
Salinomycin induces apoptosis and senescence in breast cancer: Upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation
Al Dhaheri, Yusra; Attoub, Samir; Arafat, Kholoud; AbuQamar, Synan; Eid, Ali; Al Faresi, Nesreen; Iratni, Rabah... more authors ... less authors ( Elsevier , 2013 , Article)Background In the present study, we investigated the effect of Salinomycin on the survival of three human breast cancer cell lines MCF-7, T47D and MDA-MB-231 grown in adherent culture conditions. Methods Cell viability ... -
Thromboinflammatory Processes at the Nexus of Metabolic Dysfunction and Prostate Cancer: The Emerging Role of Periprostatic Adipose Tissue
Alzaim, Ibrahim; Al-Saidi, Aya; Hammoud, Safaa H.; Darwiche, Nadine; Al-Dhaheri, Yusra; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( MDPI , 2022 , Article)The increased global prevalence of metabolic disorders including obesity, insulin resistance, metabolic syndrome and diabetes is mirrored by an increased incidence of prostate cancer (PCa). Ample evidence suggests that ... -
Towards the Pharmacological Validation and Phytochemical Profiling of the Decoction and Maceration of Bruguiera gymnorhiza (L.) Lam.-A Traditionally Used Medicinal Halophyte
Bibi Sadeer, Nabeelah; Sinan, Kouadio I.; Cziáky, Zoltán; Jekő, József; Zengin, Gokhan; Jeewon, Rajesh; Abdallah, Hassan H.; AlDhaheri, Yusra; Eid, Ali H.; Mahomoodally, Mohamad F.... more authors ... less authors ( MDPI , 2022 , Article)Decoctions (leaves and roots) of Bruguiera gymnorhiza (L.) Lam. are traditionally used against diabetes in many countries, including Mauritius. This study endeavoured to evaluate the inhibitory potential of leaves, roots, ... -
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
Dakroub, Ali; A Nasser, Suzanne; Younis, Nour; Bhagani, Humna; Al-Dhaheri, Yusra; Pintus, Gianfranco; Eid, Assaad A.; El-Yazbi, Ahmed F.; Eid, Ali H.... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ... -
Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros
Mesmar, J.; Mesmar, Joelle; Fardoun, Manal M.; Abdallah, Rola; Al Dhaheri, Yusra; Yassine, Hadi M.; Iratni, Rabah; Badran, Adnan; Eid, Ali H.; Baydoun, Elias... more authors ... less authors ( MDPI AG , 2021 , Article)Pancreatic cancer (PC) is the fourth leading cause of all cancer-related deaths. Despite major improvements in treating PC, low survival rate remains a major challenge, indicating the need for alternative approaches, ...