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AuthorVranic, Semir
AuthorGatalica, Zoran
Available date2019-04-08T11:30:07Z
Publication Date2017-12-11
Publication NameEncyclopedia of Pathologyen_US
CitationVranic S., Gatalica Z. (2018) Apocrine Carcinoma. In: van Krieken J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham
AbstractCarcinoma with apocrine differentiation (invasive apocrine carcinoma) is defined by “WHO Classification of Tumours of the Breast” as “any invasive carcinoma in which cells show the cytological features of apocrine cells” (O’Malley and Lakhani 2012). More strictly, it is a breast cancer characterized by apocrine morphology (abundant eosinophilic and granular cytoplasm, centrally/eccentrically located nuclei with prominent nucleoli and distinct cell borders) and a distinct steroid receptor profile: Estrogen receptor (ER)-negative and androgen receptor (AR)- positive cells (Vranic et al. 2013).
PublisherSpringer, Cham
SubjectBreast cancer
SubjectApocrine carcinoma
SubjectAndrogen receptor
SubjectCarcinoma with apocrine differentiation
SubjectInvasive apocrine carcinoma
TitleApocrine Carcinoma
TypeBook chapter

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