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المؤلفSalman, Huseyin Enes
المؤلفYazicioglu, Yigit
تاريخ الإتاحة2019-08-26T11:23:30Z
تاريخ النشر2019-08-01
اسم المنشورMedical Engineering and Physicsen_US
المعرّفhttp://dx.doi.org/10.1016/j.medengphy.2019.06.007
الاقتباسSalman HE, Yazicioglu Y. Computational analysis for non-invasive detection of stenosis in peripheral arteries. Med Eng Phys. 2019 Aug;70:39-50. doi: 10.1016/j.medengphy.2019.06.007.
الرقم المعياري الدولي للكتاب0946-7076
معرّف المصادر الموحدhttp://hdl.handle.net/10576/11722
الملخصAtherosclerosis usually affects the entire cardiovascular system, including peripheral blood vessels. Peripheral arterial stenosis may indicate possible serious vascular disorders related to more vital organs. If peripheral arterial stenosis can be discerned at an early stage, it can serve as a warning sign to take precautions, such as using more invasive diagnostic techniques or adopting a healthier life style. In this study, peripheral regions, such as the thigh, upper arm, and neck are modelled considering stenosis of their major arteries. Stenosis generates a fluctuating pressure field on the arterial wall, which leads to vibration on the skin's surface. This stenosis-induced pressure field is modelled as a harmonic load and applied to the inner surface of the arterial structure. The vibration response on bare skin is computationally determined using the superposition of modal responses. Realistic geometries and hyperelastic material properties are used in modelling the layers of skin, fat, muscle, and bones. The results indicate that stenosis severities higher than 70% lead to a considerable increase in vibration-response amplitudes, especially at frequencies greater than 250 Hz. The detailed analysis of skin responses provides useful information to detect the stenosis location, where the sum of the vibration amplitudes attains its maximum value around the stenosis.
راعي المشروعThis work is internally supported by Middle East Technical University (METU) Scientific Research Project (BAP) under grant number BAP-03-02-2015-006. The authors would like to thank BTech Innovation (Ankara, Turkey) for providing technical support for the reconstruction of the three-dimensional models. The authors would also like to acknowledge the financial support from the Turkish Scientific and Technical Research Council (TUBITAK) under the 2211/C program.
اللغةen
الناشرElsevier
الموضوعAtherosclerosis
الموضوعBiomechanics
الموضوعModal analysis
الموضوعStenosis
الموضوعTurbulence-induced vibration
العنوانComputational analysis for non-invasive detection of stenosis in peripheral arteries.
النوعArticle
الصفحات39-50
رقم المجلد70
ESSN1432-1858


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