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AuthorAl Moustafa, Ala-Eddin
AuthorAl-Antary, Noor
AuthorAboulkassim, Tahar
AuthorAkil, Nizar
AuthorBatist, Gerald
AuthorYasmeen, Amber
Available date2019-10-16T07:30:39Z
Publication Date2016-07-02
Publication NameHuman Vaccines & Immunotherapeuticsen_US
Identifierhttp://dx.doi.org/10.1080/21645515.2016.1139255
CitationAla-Eddin Al Moustafa, Noor Al-Antary, Tahar Aboulkassim, Nizar Akil, Gerald Batist & Amber Yasmeen (2016) Co-prevalence of Epstein–Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer, Human Vaccines & Immunotherapeutics, 12:7, 1936-1939, DOI: 10.1080/21645515.2016.1139255
ISSN2164-5515
URIhttp://hdl.handle.net/10576/12130
AbstractABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we report that EBV and high-risk HPVs are co-present in breast cancer in Syrian women. Therefore, and based on our previous studies and present data, we reveal that 35 (32%) of 108 cancer samples are positive for both EBV and high-risk HPVs and their co-presence is associated with high grade invasive ductal carcinomas (IDCs) with at least one positive lymph nodes, in comparison with EBV and high-risk HPVs-positive samples, which are low to intermediate grade IDCs, respectively. Future studies are needed to confirm the co-presence and the cooperation effect of these onco-viruses in human breast carcinogenesis and metastasis.
SponsorThis work was supported by the Canadian Institutes for Health Research (CIHR) and the Fonds de la Recherche en Santé du Québec (FRSQ- Réseau du Cancer). The new research lab of Dr. Al Moustafa is supported by the College of Medicine at Qatar University.
Languageen
PublisherTaylor & Francis
SubjectEBV
SubjectSyrian women
Subjectbreast cancer
Subjectcancer phenotype
Subjecthigh-risk HPV
TitleCo-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
TypeArticle
Pagination1936–1939
Issue Number7
Volume Number12
ESSN2164-554X


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