Browsing COVID-19 Research by Author "Eid, Ali H."
Now showing items 1-11 of 11
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Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19
Issa, Hawraa; Eid, Ali H.; Berry, Bassam; Takhviji, Vahideh; Khosravi, Abbas; Mantash, Sarah; Nehme, Rawan; Hallal, Rawan; Karaki, Hussein; Dhayni, Kawthar; Faour, Wissam H.; Kobeissy, Firas; Nehme, Ali; Zibara, Kazem... more authors ... less authors ( Frontiers , 2021 , Article)Coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the most concerning health problem worldwide. SARS-CoV-2 infects cells by binding to ... -
Could antigen presenting cells represent a protective element during sars-cov-2 infection in children?
Lauro, Rita; Irrera, Natasha; Eid, Ali H.; Bitto, Alessandra ( MDPI , 2021 , Article)Antigen Presenting Cells (APC) are immune cells that recognize, process, and present antigens to lymphocytes. APCs are among the earliest immune responders against an antigen. Thus, in patients with COVID-19, a disease ... -
Covid-19 in pediatric patients: A focus on CHD patients
Zareef, Rana O.; Younis, Nour K.; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam ( Frontiers Media S.A. , 2020 , Article)Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ... -
COVID-19: potential therapeutics for pediatric patients
Younis, Nour K.; Zareef, Rana O.; Fakhri, Ghina; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam... more authors ... less authors ( Springer , 2021 , Article Review)The global spread of COVID-19 has imparted significant economic, medical, and social burdens. Like adults, children are affected by this pandemic. However, milder clinical symptoms are often experienced by them. Only a ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
Nasarallah, Gheyath K.; Fakhroo, Aisha D.; Khan, Taushif; Cyprian, Farhan S.; Al Ali, Fatima; Ata, Manar M.A.; Taleb, Sara; Zedan, Hadeel T.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Hssain, Ali A.; Eid, Ali H.; Abu-Raddad, Laith J.; Al-Khal, Abdullatif; Al Thani, Asmaa A.; Marr, Nico; Yassine, Hadi M.... more authors ... less authors ( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
Hammoud, Safaa H.; Wehbe, Zena; Abdelhady, Samar; Kobeissy, Firas; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( American Society for Pharmacology and Experimental Therapy , 2021 , Article Review)ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ... -
Hydroxychloroquine in COVID-19 Patients: Pros and Cons
Younis, Nour K.; Zareef, Rana O.; Al Hassan, Sally N.; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam... more authors ... less authors ( Frontiers Media S.A. , 2020 , Article)The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach ... -
Macrophage responses associated with COVID-19: A pharmacological perspective
Booz, George W.; Altara, Raffaele; Eid, Ali H.; Wehbe, Zena; Fares, Souha; Zaraket, Hassan; Habeichi, Nada J.; Zouein, Fouad A.... more authors ... less authors ( Elsevier , 2020 , Article)COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ... -
Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality
Wehbe, Zena; Hammoud, Safaa Hisham; Yassine, Hadi M; Fardoun, Manal; El-Yazbi, Ahmed F; Eid, Ali H... more authors ... less authors ( Frontiers Media , 2021 , Article)Globally, over two million people have perished due to the recent pandemic caused by SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher rate of severity and mortality in males. Analyzing ... -
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
Wehbe, Zena; Hammoud, Safaa; Soudani, Nadia; Zaraket, Hassan; El-Yazbi, Ahmed; Eid, Ali H.... more authors ... less authors ( Frontiers Media S.A. , 2020 , Article)In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV ... -
Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities
Wehbe, Zena; Wehbe, Maya; Iratni, Rabah; Pintus, Gianfranco; Zaraket, Hassan; Yassine, Hadi M; Eid, Ali H... more authors ... less authors ( Frontiers Media , 2021 , Article)As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID-19. Several vaccines, including mRNA, ...