Browsing Academic by Subject "Metabolism"
Now showing items 1-12 of 12
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Between Immunity, Metabolism, and Development: A story of a Fly Gut!
( Qatar University Press , 2020 , Poster)In addition to its role in initiating immune response in the body, the innate immune system seems to also play a critical role in maintaining homeostatic balance in the gut epithelium. Our recent studies in the Drosophila ... -
Correction to: Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment (Cancer Immunology, Immunotherapy, (2021), 70, 8, (2103-2121), 10.1007/s00262-020-02842-y)
( Springer , 2021 , Other)in the hypoxic tumor microenvironment, written by Varun Sasidharan Nair, Reem Saleh, Salman M. Toor, Farhan S. Cyprian and Eyad Elkord, was originally published electronically on the publisher’s internet portal on 03 ... -
MDM2- an indispensable player in tumorigenesis
( Springer Science and Business Media B.V. , 2023 , Article Review)Murine double minute 2 (MDM2) is a well-recognized molecule for its oncogenic potential. Since its identification, various cancer-promoting roles of MDM2 such as growth stimulation, sustained angiogenesis, metabolic ... -
Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment.
( Springer , 2021 , Article)Metabolic dysregulation in the hypoxic tumor microenvironment (TME) is considered as a hallmark of solid tumors, leading to changes in biosynthetic pathways favoring onset, survival and proliferation of malignant cells. ... -
Multiscale denoising of biological data: A comparative analysis
( IEEE , 2012 , Article)Abstract: Measured microarray genomic and metabolic data are a rich source of information about the biological systems they represent. For example, time-series biological data can be used to construct dynamic genetic ... -
Role of NAD+ in regulating cellular and metabolic signaling pathways
( Elsevier , 2021 , Article Review)BackgroundNicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD+ is often ... -
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.
( Nature Research , 2021 , Article)The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. ... -
THE ROLE OF ENTEROENDOCRINE SECRETED GUT PEPTIDE HORMONES IN MODULATING IMMUNITY AND METABOLISM IN DROSOPHILA MELANOGASTER
(2021 , Master Thesis)The intestine of all living organisms fosters an ecosystem of commensal microbiota that plays key roles in the maintenance of host health and pathology. Captivatingly, the influence of dysbiosis on the host has demonstrated ... -
THE USE OF DROSOPHILA MELANOGASTER AS A MODEL ORGANISM TO STUDY THE EFFECT OF BACTERIAL INFECTION ON HOST SURVIVAL AND METABOLISM
( Qatar University Press , 2020 , Poster)Enterobacteriaceae, a large family of facultative anaerobic bacteria, encloses a broad spectrum of bacterial species including Escherichia coli, Salmonella enterica, and Shigella sonnei, that produce enterotoxins and ... -
The Use of Drosophila Melanogaster as A Model Organism To Study The Effect Of Innate Immunity On Metabolism
( Qatar University Press , 2020 , Poster)Apart from its traditional role in disease control, recent body of evidence has implicated a role of the immune system in regulating metabolic homeostasis. Owing to the importance of this “immune-metabolic alignment” ... -
Wavelet-based multiscale filtering of genomic data
( IEEE Computer Society , 2012 , Conference Paper)Measured biological data are a rich source of information about the biological phenomena they represent. For example, time-series genomic or metabolic microarray data can be used to construct dynamic genetic regulatory ... -
Yerba Maté (Illex Paraguariensis) ingestion augments fat oxidation and energy expenditure during exercise at various submaximal intensities
( BioMed Central , 2014 , Article)Background Ingesting Yerba Maté (YM) has become widely popular for health promotion, obesity prevention and body weight reduction, primarily due its thermogenic effectiveness. However, the YM effects on fat metabolism ...