Browsing Medicine Research by Subject "DNA damage"
Now showing items 1-3 of 3
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DNA Damage/Repair Management in Cancers
( MDPI , 2020 , Article Review)DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA ... -
DNA Damage/Repair Management in Cancers
( Routledge , 2021 , Book chapter)DNA damage can alter nucleotide sequences and lead to expression of dysfunctional proteins that impact normal cellular physiology. Sources of DNA damage can be endogenous or exogenous and include reactive oxygen species ... -
Targeting DNA Repair Pathways in Hematological Malignancies.
( MDPI , 2020 , Article Review)DNA repair plays an essential role in protecting cells that are repeatedly exposed to endogenous or exogenous insults that can induce varying degrees of DNA damage. Any defect in DNA repair mechanisms results in multiple ...