Browsing Medicine Research by Subject "Whole genome sequencing"

Now showing items 1-2 of 2

    • A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic. 

      Klopper, Marisa; Heupink, Tim Hermanus; Hill-Cawthorne, Grant; Streicher, Elizabeth Maria; Dippenaar, Anzaan; ... more authors ( BMC , 2020 , Article)
      Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and ...

    • What is the right sequencing approach? Solo VS extended family analysis in consanguineous populations. 

      Alfares, Ahmed; Alsubaie, Lamia; Aloraini, Taghrid; Alaskar, Aljoharah; Althagafi, Azza; ... more authors ( Springer Nature , 2020 , Article)
      Testing strategies is crucial for genetics clinics and testing laboratories. In this study, we tried to compare the hit rate between solo and trio and trio plus testing and between trio and sibship testing. Finally, we ...