Browsing Medicine Research by Subject "colorectal cancer"
Now showing items 1-10 of 10
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Co-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.
( Taylor & Francis , 2020 , Article)We recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, ... -
Coinfection of HPVs Is Associated with Advanced Stage in Colorectal Cancer Patients from Qatar
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)High-risk human papillomaviruses (HPVs) are considered risk factors in the origin of several human malignancies, such as breast, cervical, head and neck, as well as colorectal cancers. However, there are no data reported ... -
Copresence of High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer: A Tissue Microarray and Molecular Study from Lebanon
( MDPI , 2021 , Article)Colorectal cancer (CRC) is the third most common cause of cancer-related deaths worldwide. Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) have been reported to be present in different types of human cancers ... -
High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer.
( Spandidos Publications , 2020 , Article)Adoptive cell therapy with the use of tumor-infiltrating lymphocytes (TILs) is a very promising immunotherapeutic approach for the treatment of patients with colorectal cancer (CRC). However, within the tumor microenvironment, ... -
High-Risk Human Papillomaviruses (HPV) and Epstein - Barr virus (EBV) are Commonly Present in Rectal Cancer
( Springer Nature , 2020 , Conference Paper)Background: Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) are well-established oncoviruses that can be co-present and cooperate in the initiation and/or progression of various human cancers. We recently reported ... -
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
( MDPI , 2020 , Article)Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ... -
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
( MDPI , 2022 , Article Review)The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ... -
Immunotherapy and immunoevasion of colorectal cancer
( Elsevier , 2023 , Article Review)The tremendous success of immunotherapy in clinical trials has led to its establishment as a new pillar of cancer therapy. However, little clinical efficacy has been achieved in microsatellite stable colorectal cancer ... -
Molecular correlates of immune cytolytic subgroups in colorectal cancer by integrated genomics analysis
( Oxford University Press , 2021 , Article)Although immune checkpoint inhibition (ICI) has shown promising results in metastatic dMMR/MSI-H colorectal cancer (CRC), the majority of pMMR/MSS patients do not respond to such therapies. To systematically evaluate the ... -
Signatures of co-deregulated genes and their transcriptional regulators in colorectal cancer.
( Nature Research , 2020 , Article)The deregulated genes in colorectal cancer (CRC) vary significantly across different studies. Thus, a systems biology approach is needed to identify the co-deregulated genes (co-DEGs), explore their molecular networks, and ...