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The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
(
MDPI AG
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Meta-analysis of intracavitary electrocardiogram guidance for peripherally inserted central catheter placement
(
SAGE Publications Ltd
, 2019 , Article Review)
Background:
Recently, intracavitary electrocardiogram technology has been applied to peripherally inserted central catheter placement and demonstrates many potential advantages. However, the tip positioning accuracy of ...
Targeted immunotherapy with a checkpoint inhibitor in combination with chemotherapy: A new clinical paradigm in the treatment of triple-negative breast cancer.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2019 , Article Review)
The treatment of several solid and hematologic malignancies with immune checkpoint inhibitors (against PD-1/PD-L1) has dramatically changed the cancer treatment paradigm. However, no checkpoint inhibitors were previously ...
Fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in castration-resistant prostate cancer cells: a potential therapeutic target
(
Oxford University Press
, 2019 , Article Review)
In this short communication, a novel fatty acid-binding protein 5 (FABP5)-related signal transduction pathway in
prostate cancer is reviewed. In castration-resistant prostate cancer (CRPC) cells, the FABP5-related signal ...
Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
(
Wiley
, 2019 , Article Review)
Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ...
Lichen planus: a comprehensive evidence-based analysis of medical treatment
(
Blackwell Publishing Ltd
, 2019 , Article Review)
Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ...
Safety and efficacy of leadless pacemaker retrieval
(
Blackwell Publishing Inc.
, 2019 , Article Review)
Background and Objectives: The success rate of leadless cardiac pacemaker (LP) retrieval remains a major concern for this disruptive technology. The present paper performed a systematic review of the safety and feasibility ...
Giant parathyroid adenoma: A case report and review of the literature
(
BioMed Central Ltd.
, 2019 , Article Review)
Background: Giant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical ...
Targeting inflammatory components in neuropathic pain: The analgesic effect of thymulin related peptide
(
Elsevier Ireland Ltd
, 2019 , Article Review)
Neuropathic pain is considered to be pathological in nature and has been shown to involve, at least partially, dysregulated inflammatory processes. It is a severe chronic disease that can develop following lesions to the ...
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
(
Springer Healthcare
, 2019 , Article Review)
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ...