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Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
(
Wiley
, 2019 , Article Review)
Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ...
Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis
(
Blackwell Publishing Ltd
, 2019 , Article)
Background
When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. The hypoxia‐inducible ...
Lichen planus: a comprehensive evidence-based analysis of medical treatment
(
Blackwell Publishing Ltd
, 2019 , Article Review)
Lichen planus (LP) is a chronic-relapsing inflammatory skin disease. Although many drugs have been used for the management of LP, some of them lack the backup by strong therapeutic evidence, while others are not suitable ...
Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond.
(
Frontiers Media
, 2019 , Article)
In addition to its role in calcium homeostasis and bone formation, a modulatory role of the active form of vitamin D on cells of the immune system, particularly T lymphocytes, has been described. The effects of vitamin D ...
Somatostatin receptor SSTR2A and SSTR5 expression in neuroendocrine breast cancer.
(
Elsevier
, 2019 , Article)
Neuroendocrine breast cancer (NEBC) is a group of rare tumors, which could benefit from therapy targeting the somatostatin receptors (SSTRs). In particular, SSTR2A and SSTR5 are potential targets given their consistent ...
Mucocele of the appendix presenting as an exacerbated chronic tubo-ovarian abscess: A case report and comprehensive review of the literature.
(
Lippincott, Williams & Wilkins
, 2019 , Article)
Appendiceal mucocele is a rare entity of mucinous cystic dilatation of the appendix. It has no typical clinical presentation and is considered a potentially premalignant condition. We present a case of accidental intraoperative ...
Molecular profiling reveals novel targetable biomarkers in neuroendocrine carcinoma of the uterine cervix
(
Oxford University Press
, 2019 , Conference Paper)
Background
Neuroendocrine carcinoma of the uterine cervix (NEC) is a rare cervical malignancy, accounting for 0.9% of all cervical carcinomas. Cervical NEC is a high-grade cancer with an aggressive clinical course and ...
Development of discriminant functions to estimate sex in upper limb bones for mixed ancestry South Africans
(
Elsevier
, 2019 , Article)
The Chartered Society of Forensic Sciences South Africa has one of the highest murder rates in the world, which is associated with an increasing number of unidentified individuals. Forensic anthropologists can assist in ...
Safety and efficacy of leadless pacemaker retrieval
(
Blackwell Publishing Inc.
, 2019 , Article Review)
Background and Objectives: The success rate of leadless cardiac pacemaker (LP) retrieval remains a major concern for this disruptive technology. The present paper performed a systematic review of the safety and feasibility ...
Letter to Editor: Apocrine carcinoma is the fact. Comment on the recent paper entitled "Invasive apocrine carcinoma of the breast: Myth or fact?" by Gurrado et al (Breast J. 2019 Sep 8. doi: 10.1111/tbj.13569. [Epub ahead of print].
(
Wiley
, 2019 , Article)
The most recent WHO classification of breast cancer also recognizes the concept of “pure apocrine carcinoma” (called carcinoma with apocrine differentiation) with cancers having >90% of apocrine morphology (an essential ...