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Recent Submissions

  • Characterising Alzheimer's disease through integrative NMR- and LC-MS-based metabolomics 

    Jonas Ellegaard, Nielsen; Maltesen, Raluca Georgiana; Havelund, Jesper F.; Færgeman, Nils J.; Gotfredsen, Charlotte Held; ... more authors ( Elsevier , 2021 , Article)
    BackgroundAlzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein ...

  • Shotgun-based proteomics of extracellular vesicles in Alzheimer’s disease reveals biomarkers involved in immunological and coagulation pathways 

    Nielsen, Jonas Ellegaard; Honoré, Bent; Vestergård, Karsten; Maltesen, Raluca Georgiana; Christiansen, Gunna; ... more authors ( Nature Research , 2021 , Article)
    Alzheimer’s disease (AD) is the most common form of dementia and without readily available clinical biomarkers. Blood-derived proteins are routinely used for diagnostics; however, comprehensive plasma profiling is challenging ...

  • Numerical parametric investigation on the moment redistribution of basalt FRC continuous beams with basalt FRP bars 

    Abushanab, Abdelrahman; Alnahhal, Wael ( Elsevier , 2021 , Article)
    Recently, researchers’ efforts have been directed toward using fiber-reinforced concrete (FRC) in lieu of conventional concrete to improve the compressive strain, tensile strength capacity, cracking patterns, and ductility ...

  • Waning of BNT162b2 Vaccine Protection against SARS-CoV-2 Infection in Qatar. 

    Chemaitelly, Hiam; Tang, Patrick; Hasan, Mohammad R; AlMukdad, Sawsan; Yassine, Hadi M; ... more authors ( Massachusetts Medical Society , 2021 , Article)
    Waning of vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (Covid-19) is a concern. The persistence of BNT162b2 (Pfizer-BioNTech) vaccine ...

  • Identifying metabolic alterations in newly diagnosed small cell lung cancer patients 

    Shona, Pedersen; Hansen, Joachim Bavnhøj; Maltesen, Raluca Georgiana; Szejniuk, Weronika Maria; Andreassen, Trygve; ... more authors ( Elsevier , 2021 , Article)
    BackgroundSmall cell lung cancer (SCLC) is a malignant disease with poor prognosis. At the time of diagnosis most patients are already in a metastatic stage. Current diagnosis is based on imaging, histopathology, and ...

  • Pfizer-BioNTech mRNA BNT162b2 Covid-19 vaccine protection against variants of concern after one versus two doses. 

    Abu-Raddad, Laith J; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; Al Khatib, Hebah A; ... more authors ( Oxford University Press , 2021 , Article)
    Strategies for rolling out vaccination against Coronavirus Disease 2019 (Covid-19) varied across countries. A key question is whether delaying administration of the second vaccine dose to vaccinate the largest number of ...

  • The impact of teacher preparation on preservice teachers' attitudes toward inclusive education in Qatar 

    E.A. Hassanein, Elsayed; M. Alshaboul, Yousef; Ibrahim, Sayed ( Elsevier , 2021 , Article)
    Teachers' beliefs and attitudes are a significant component in the development and success of inclusive education. Research indicates that the foundation of positive attitudes toward inclusive education can be established ...

  • How circular design can contribute to social sustainability and legacy of the FIFA World Cup Qatar 2022™? The case of innovative shipping container stadium 

    Kucukvar, Murat; A. Kutty, Adeeb; Al-Hamrani, Abathar; Kim, Doyoon; Nofal, Nadejhda; ... more authors ( Elsevier , 2021 , Article)
    The circular economy proposes a paradigm shift from the ‘take-make-waste’ type of economic system and aims to foster innovation, resource efficiency, and waste prevention. Mega sporting events can be considered great ...

  • SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy 

    Laith J., Abu-Raddad; Chemaitelly, Hiam; Coyle, Peter; Malek, Joel A.; Ahmed, Ayeda A.; ... more authors ( Elsevier , 2021 , Article)
    BackgroundReinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons ...

  • mRNA-1273 COVID-19 vaccine effectiveness against the B.1.1.7 and B.1.351 variants and severe COVID-19 disease in Qatar 

    Chemaitelly, Hiam; Yassine, Hadi M.; Benslimane, Fatiha M.; Al Khatib, Hebah A.; Tang, Patrick; ... more authors (2021 , Article)
    The SARS-CoV-2 pandemic continues to be a global health concern. The mRNA-1273 (Moderna) vaccine was reported to have an efficacy of 94.1% at preventing symptomatic COVID-19 due to infection with ‘wild-type’ variants in a ...

  • Gender and Return Migration: Gulf Returnees in Ghana 

    Rahman, Md Mizanur; Salisu, Mohammed ( College of Arts and Sciences - Gulf Studies Center , 2021 , Working Paper)
    Labor migration in the Global South is generally conceived as a multidimensional process that comprises three distinct subprocesses: emigration, immigration, and return migration. There is growing consensus that return ...

  • COVID-19 and Migrants in the GCC states: Challenges, responses and key lessons 

    Rahman, Md Mizanur ( College of Arts and Sciences - Gulf Studies Center , 2021 , Working Paper)
    As the COVID-19 pandemic unfolds, the GCC countries face an unprecedented challenge of controlling the spiralling COVID-19 cases. The challenge has become even more formidable in containing the virus among non-national ...

  • Epidemiological impact of prioritising SARS-CoV-2 vaccination by antibody status: Mathematical modelling analyses 

    Ayoub, H.H.; Ayoub, Houssein H.; Chemaitelly, Hiam; Makhoul, Monia; Al Kanaani, Zaina; ... more authors ( BMJ Publishing Group , 2021 , Article)
    Background Vaccines against SARS-CoV-2 have been developed, but their availability falls far short of global needs. This study aimed to investigate the impact of prioritising available doses on the basis of recipient ...

  • SARS-CoV-2 seroprevalence in the urban population of Qatar: An analysis of antibody testing on a sample of 112,941 individuals 

    Peter V., Coyle; Chemaitelly, Hiam; Ben Hadj Kacem, Mohamed Ali; Abdulla Al Molawi, Naema Hassan; El Kahlout, Reham Awni; ... more authors ( Elsevier , 2021 , Article)
    The study objective was to the assess level of detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the urban population of Qatar. Antibody testing was performed on residual blood specimens ...

  • SARS-CoV-2 Infection Is at Herd Immunity in the Majority Segment of the Population of Qatar. 

    Al-Thani, Mohamed H; Farag, Elmoubasher; Bertollini, Roberto; Al Romaihi, Hamad Eid; Abdeen, Sami; ... more authors ( Oxford University Press , 2021 , Article)
    Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population, who comprise 60% of the total population. This study ...

  • Mechanical and durability properties of ultra-high performance steel FRC made with discarded materials 

    Abushanab, Abdelrahman; Ghous Sohail, Muazzam; Alnuaimi, Nasser; Kahraman, Ramazan; Altayeh, Nezam ( Elsevier , 2021 , Article)
    This study investigates the mechanical and durability properties of 12 ultra-high performance fiber reinforced concrete (UHPFRC) mixes manufactured using alternate aggregate sources. Natural gabbro aggregates (GA), steel ...

  • Calmodulin Interacts and Regulates Enzyme Activity of the Mammalian Sperm Phospholipase C 

    Nomikos, Michail; Thanassoulas, Angelos; L. Calver, Brian; Theodoridou, Maria; Buntwal, Luke; ... more authors ( Elsevier , 2017 , Article)
    Sperm-specific Phospholipase C zeta (PLCζ) is widely considered to be the sole, physiological stimulus responsible for the generation of Ca2+ oscillations that induce egg activation and early embryo development during ...

  • The Arrhythmogenic E105A CAM Mutation Dysregulates Normal Cardiac Function in Zebrafish by Altering CAM-Ca2+ and CAM-RyR2 Interactions 

    Nomikos, Michail; I. Da’as, Sahar; Thanassoulas, Angelos; Salem, Rola; L. Calver, Brian; ... more authors ( Elsevier , 2019 , Article)
    Calmodulin (CaM) is a multifunctional calcium (Ca2+)-binding messenger that directly interacts with the cardiac ryanodine receptor 2 (RyR2), a large transmembrane Ca2+ channel that mediates Ca2+ release from the sarcoplasmic ...

  • Defective Interaction of Cam with RyR2 Cam-Binding Pocket Might Contribute to Arrhythmogenic Cardiac Disease 

    Nomikos, Michail; Thanassoulas, Angelos; Vassilakopoulou, Vyronia; L. Calver, Brian; Livaniou, Evangelia; ... more authors ( Elsevier , 2020 , Article)
    Ryanodine receptor 2 (RyR2) is a large transmembrane calcium (Ca2+) release channel that mediates Ca2 release from the sarcoplasmic reticulum to activate cardiac muscle contraction. Calmodulin (CaM) regulation of RyR2 is ...

  • Large eddy simulation of surge inception and active surge control in a high speed centrifugal compressor with a vaned diffuser 

    Shahin, Ibrahim; Alqaradawi, Mohamed; Gadala, Mohamed; Badr, Osama ( Elsevier , 2016 , Article)
    In this study, we present a numerical investigation of active surge control and performance improvement for an aero engine centrifugal compressor (NASA CC3) using self-recirculating bleed slots with different bleeding ...

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