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Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
(
MDPI
, 2020 , Article Review)
Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
Growing Burden of Hypertension in China: Causes, Challenges, and Opportunities
(
Chinese Center for Disease Control and Prevention (China CDC)
, 2020 , Article Review)
Cardiovascular disease (CVD) is the leading cause of
death in China, and an estimated 290 million
individuals are affected by CVD in China (1).
Hypertension is the most important risk factor of
CVD (2). Good control ...
Better reporting standards are needed to enhance the quality of hop testing in the setting of ACL return to sport decisions: a narrative review.
(
BMJ Publishing Group
, 2020 , Article Review)
There is a lack of consistency in return to sport (RTS) assessments, in particular hop tests to predict who will sustain a reinjury following anterior cruciate ligament (ACL) reconstruction. Inconsistent test battery content ...
Targeting DNA Repair Pathways in Hematological Malignancies.
(
MDPI
, 2020 , Article Review)
DNA repair plays an essential role in protecting cells that are repeatedly exposed to endogenous or exogenous insults that can induce varying degrees of DNA damage. Any defect in DNA repair mechanisms results in multiple ...
Nanostructured Metal Oxide-Based Acetone Gas Sensors: A Review.
(
MDPI
, 2020 , Article Review)
Acetone is a well-known volatile organic compound that is widely used in different industrial and domestic areas. However, it can have dangerous effects on human life and health. Thus, the realization of sensitive and ...
A Review of Clinical Pharmacokinetic and Pharmacodynamic Relationships and Clinical Implications for Drugs Used to Treat Multi-drug Resistant Tuberculosis
(
Springer
, 2020 , Article Review)
Multidrug-resistant tuberculosis (MDR-TB) is becoming a global health crisis. The World Health Organization has released new guidelines for the use of tuberculosis-active drugs for the treatment of patients with MDR-TB. ...