Search
Now showing items 81-90 of 262
Direct cardiovascular impact of SGLT2 inhibitors: mechanisms and effects
(
Springer New York LLC
, 2018 , Article Review)
Diabetes is a global epidemic and a leading cause of death with more than 422 million patients worldwide out of whom around 392 million alone suffer from type 2 diabetes (T2D). Sodium-glucose cotransporter 2 inhibitors ...
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
(
Springer-Verlag France
, 2018 , Article Review)
Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ...
Retinopathy of Type 1 Diabetes in Arab Countries: Systematic Review and Meta-Analysis.
(
Karger
, 2018 , Article Review)
To conduct a systematic review and meta-analysis of retinopathy prevalence in patients with type 1 diabetes (T1D) in 22 Arab countries. We systematically searched 4 different literature databases (PubMed, Science Direct, ...
Italo-Australian Transnational Houses: Critical Review of a Qualitative Research Study
(
OMICS International
, 2015 , Article Review)
The research study aimed to understand how first generation Italian migrants in Brisbane have influenced the form of a specific typology of dwelling, the archetypal ‘house on a quarter-acre block’, in the post WWII period.
In ...
Towards understanding the mechanisms of actions of carcinoembryonic antigen-related cell adhesion molecule 6 in cancer progression
(
Wiley Open Access
, 2017 , Article Review)
Human carcinoembryonic antigen (CEA) is the prototypic member of a family of
highly related cell surface glycoproteins that includes carcinoembryonic antigenrelated
cell adhesion molecule 6 (CEACAM6) and others. CEACAM6 ...
The physiological effects of concurrent strength and endurance training sequence: A systematic review and meta-analysis.
(
Taylor & Francis
, 2017 , Article Review)
We conducted a systematic literature review and meta-analysis to assess the chronic effects of the sequence of concurrent strength and endurance training on selected important physiological and performance parameters, ...
Novel CD44-downstream signaling pathways mediating breast tumor invasion
(
Ivyspring International Publisher
, 2018 , Article Review)
CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell
and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways,
including ...
Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine.
(
Nature Research
, 2018 , Article Review)
The gene-environment interactions resulting from famine and the subsequent increased intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current epidemic of T2DM in China, which poses major ...
The Dual Specificity Role of Transcription Factor FOXO in Type 2-diabetes and Cancer
(
Bentham Science Publishers
, 2018 , Article Review)
The FOXO (Forkhead box O) transcription factors are implicated in several signaling pathways and play a vital role in various cellular and physiological processes include for instance, ROS (reactive oxygen species) response, ...
Epstein-Barr Virus in Gliomas: Cause, Association, or Artifact?
(
Frontiers Media
, 2018 , Article Review)
Gliomas are the most common malignant brain tumors and account for around 60% of all primary central nervous system cancers. Glioblastoma multiforme (GBM) is a grade IV glioma associated with a poor outcome despite recent ...