• Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling 

      Maayah, Zaid H.; Ferdaoussi, Mourad; Boukouris, Aristeidis E.; Takahara, Shingo; Das, Subhash K.; ... more authors ( Elsevier , 2023 , Article)
      Background: Although some cancer therapies have overt and/or subclinical cardiotoxic effects that increase subsequent cardiovascular risk in breast cancer patients, we have recently shown that the breast tumor itself can ...
    • Myocardial proteases and cardiac remodeling 

      Riaz, Sadaf; Zeidan, Asad; Mraiche, Fatima ( Wiley-Liss Inc. , 2017 , Article Review)
      Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need ...
    • Targeting Osteopontin, the Silent Partner of Na+/H+ Exchanger Isoform 1 in Cardiac Remodeling 

      Mohamed, Iman A.; Mraiche, Fatima ( Wiley Periodicals, Inc. , 2015 , Article)
      Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, contributes to cardiac remodeling, which if left unresolved results in heart failure. Understanding the signaling pathways ...