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Cytotoxic Homoisoflavones from the Bulbs of Bellevalia eigii
(
American Chemical Society
, 2015 , Article)
Eight new and 10 known compounds were isolated from an organic extract of the bulbs of Bellevalia eigii as part of a search for anticancer leads from native plants of Jordan. Of these, the series of 16 homoisoflavonoids ...
Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals
(
Springer International Publishing
, 2014 , Article Review)
Management of HIV and malaria co-infection is challenging due to potential drug-drug interactions between antimalarial and HIV-antiviral drugs. Little is known of the clinical significance of these drug interactions, and ...
The Therapeutic Effects of Camel Milk: A Systematic Review of Animal and Human Trials
(
SAGE Publications Ltd
, 2016 , Article Review)
The clinical effectiveness and value of camel milk as a therapeutic agent is currently unclear. MEDLINE (1946 to March 2016), EMBASE (1974 to March 2016), and Google Scholar were searched using the following terms: milk, ...
Impact of a pharmacist-delivered discharge and follow-up intervention for patients with acute coronary syndromes in Qatar: A study protocol for a randomised controlled trial
(
BMJ Publishing Group
, 2016 , Article)
Introduction: Acute coronary syndrome (ACS) is one of the leading causes of morbidity and mortality worldwide. Secondary cardiovascular risk reduction therapy (consisting of an aspirin, a ?-blocker, an ACE inhibitor or an ...
Open-label study of absorption and clearance of 1% voriconazole eye drops
(
American Society for Microbiology
, 2016 , Article)
Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous ...
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European-Americans and Egyptians
(
Blackwell Publishing Ltd
, 2016 , Article)
Genotype-based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin ...
Evaluation of pharmacist-based compared to doctor-based anticoagulation management in Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives For over 60 years, warfarin has been the mainstay anticoagulant used in the outpatient setting for the prevention and treatment of a wide variety of thromboembolic clinical conditions. ...
Targeting dopaminergic system for treating nicotine dependence
(
Bentham Science Publishers B.V.
, 2016 , Article)
Background: Smoking is the world's leading cause of preventable death among populations. Cigarette smoking increases the risk of numerous health problems, including heart diseases, stroke, atherosclerosis and many types ...
Role of pharmacist in cardiovascular disease-related health promotion and in hypertension and dyslipidemia management: A cross-sectional study in the State of Qatar
(
Blackwell Publishing Ltd
, 2016 , Article)
Rationale, aims and objectives In Qatar, cardiovascular diseases (CVD) have recently become the leading cause of morbidity and mortality. Prevention, detection and management of CVD risk factors reduce CVD chance. The study ...