Browsing Mechanical & Industrial Engineering by Subject "Blood-brain barrier"
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Bioengineered microfluidic blood-brain barrier models in oncology research
( Neoplasia Press, Inc. , 2021 , Article)Metastasis is the major reason for most brain tumors with up to a 50% chance of occurrence in patients with other types of malignancies. Brain metastasis occurs if cancer cells succeed to cross the ?blood-brain barrier? ... -
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
( Elsevier B.V. , 2018 , Article Review)The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ...