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CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program
(
Mary Ann Liebert Inc.
, 2019 , Article)
CD28 superagonist (CD28SA), a therapeutic immunomodulatory monoclonal antibody triggered rapid and exaggerated activation of CD4+ effector memory T cells (TEMs) in humans with unwanted serious adverse effects. It is well ...