Browsing College of Medicine by Subject "Excitation-contraction coupling"
Now showing items 1-2 of 2
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Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?
( Company of Biologists Ltd , 2018 , Article)The cardiac muscle ryanodine receptor-Ca2+ release channel (RyR2) constitutes the sarcoplasmic reticulum (SR) Ca2+ efflux mechanism that initiates myocyte contraction, while cardiac myosin-binding protein-C (cMyBP-C; also ... -
Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
( Oxford University Press , 2020 , Article)The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ...