Browsing College of Medicine by Subject "Meta-analysis"
Now showing items 1-13 of 13
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Accuracy of artificial intelligence-assisted detection of Oral Squamous Cell Carcinoma: A systematic review and meta-analysis
( Elsevier , 2022 , Article)Oral Squamous Cell Carcinoma (OSCC) is an aggressive tumor with a poor prognosis. Accurate and timely diagnosis is therefore essential for reducing the burden of advanced disease and improving outcomes. In this meta-analysis, ... -
Angry scientists, angry analysts and angry novelists
( Springer Nature , 2023 , Other)To the Editor: Professor Bonora has written a critique looking back at his career in diabetes research since the 1970s and we reflect on his critique by also looking back at our careers in clinical endocrinology (Professor ... -
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
( BMC , 2018 , Article Review)Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ... -
Comparison of bias adjustment methods in meta-analysis suggests that quality effects modeling may have less limitations than other approaches.
( Elsevier , 2019 , Article)The quality of primary research is commonly assessed before inclusion in meta-analyses. Findings are discussed in the context of the quality appraisal by categorizing studies according to risk of bias. The impact of appraised ... -
Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses
( Elsevier , 2023 , Article)BackgroundDespite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine ... -
Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
( springer link , 2023 , Article)Background: Obesity is a chronic inflammatory condition and this meta-analysis evaluated the impact of bariatric surgery on SAA. Methods: Studies included all types of bariatric surgery where SAA was measured before and ... -
An integrative comparative study between ultrasound-guided regional anesthesia versus parenteral opioids alone for analgesia in emergency department patients with hip fractures: A systematic review and meta-analysis
( Elsevier , 2022 , Article Review)BackgroundEmergency physicians play a major role in managing patients with hip fractures. The most commonly used pain management option is parenteral opioids. However, parenteral opioids are subjected to several adverse ... -
Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
( BMC , 2020 , Article)© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ... -
The odds ratio is “portable” but not the relative risk: Time to do away with the log link in binomial regression
( Elsevier , 2021 , Article)Objectives: In a recent paper we suggest that the relative risk (RR) be replaced with the odds ratio (OR) as the effect measure of choice in clinical epidemiology. In response, Chu, and colleagues raise several points that ... -
P-value driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses
( Elsevier , 2019 , Article)To investigate the effect of number of studies in a meta-analysis on the detection of publication bias using p-value driven methods. The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests ... -
Should studies with no events in both arms be excluded in evidence synthesis?
( Elsevier , 2022 , Article)ObjectivesIn safety assessment, studies with no events are a frequent occurrence when conducting meta-analyses. The current approach in meta-analysis is to exclude double-zero studies from the synthesis. In this study, we ... -
Stratification by quality induced selection bias in a meta-analysis of clinical trials.
( Elsevier , 2018 , Article)The inconsistency demonstrated across strata when using different scales has been attributed to quality scores and stratification continues to be done using risk of bias domain judgments. This study examines if restricting ... -
Utilization of the evidence from studies with no events in meta-analyses of adverse events: an empirical investigation
( Springer , 2021 , Article)Zero-events studies frequently occur in systematic reviews of adverse events, which consist of an important source of evidence. We aimed to examine how evidence of zero-events studies was utilized in the meta-analyses of ...