Browsing College of Pharmacy by Title
Now showing items 1-20 of 478
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5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism
( Springer Verlag , 2016 , Article)Recent studies have established the role of mid-chain hydroxyeicosatetraenoic acids (HETEs) in the development of cardiovascular disease. Mid-chain HETEs have been reported to have vasoconstrictive and pro-inflammatory ... -
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells
( MDPI AG , 2019 , Article)Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ... -
A case of probable esomeprazole-induced transient liver injury in a pregnant woman with hyperemesis
( Dove Medical Press Ltd , 2016 , Article)We report a case of 22-year-old primigravida presented to Women�s Hospital - Hamad Medical Corporation emergency with severe epigastric pain, nausea, and vomiting. On admission, she was dehydrated with remarkably worsening ... -
A comprehensive systematic review of pharmacy perspectives on interprofessional education and collaborative practice
( Elsevier Inc. , 2018 , Article Review)Introduction: Pharmacists are key professionals in the collaborative working process and are integral members of the healthcare team. However, there is paucity of information regarding their perspectives towards interprofessional ... -
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
( Springer International Publishing , 2016 , Article Review)Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ... -
A holistic conceptual framework model to describe medication adherence in and guide interventions in diabetes mellitus
( Elsevier Inc. , 2018 , Article)BACKGROUND: Nonadherence to medications in patients with diabetes, which results in poor treatment outcomes and increased healthcare costs, is commonly reported globally. Factors associated with medication adherence have ... -
A literature-based algorithm for the assessment, management, and monitoring of drug-induced QTc prolongation in the psychiatric population
( Dove Medical Press Ltd. , 2019 , Article Review)Background: Certain psychotropics and a number of other medications used to treat medical conditions in psychiatric patients can increase the risk of prolonging the corrected QT (QTc) interval on the electrocardiogram, ... -
A psychometric analysis of a newly developed summative, multiple choice question assessment adapted from Canada to a Middle Eastern context
( Elsevier Inc. , 2018 , Article)Introduction: Accreditation necessitates that assessment methods reflect the standards established by the accrediting body. The process of adapting assessments to a new context can present unique challenges with uncertainty ... -
A qualitative exploration of clozapine prescribing and monitoring practices in the Arabian Gulf countries
( Elsevier B.V. , 2019 , Article)Clozapine is considered as the first line antipsychotic for treatment resistant schizophrenia (TRS). Worldwide reports indicate an overall underutilization of clozapine in patients experiencing TRS. This study aims to ... -
A Review of Clinical Outcomes Associated with Two Meropenem Dosing Strategies
( Springer International Publishing , 2017 , Article Review)Meropenem is a carbapenem antibiotic that exhibits time-dependent bactericidal activity, traditionally dosed intravenously at 1�g every 8�h. In order to maximize its pharmacodynamic activity and reduce costs, an alternative ... -
A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
( Springer-Verlag France , 2017 , Article Review)Genetic variability in drug-metabolizing enzymes and drug transporters is known to influence the pharmacokinetics of many drugs. Antimalarial drugs are a class of agents known to utilize metabolic and elimination pathways ... -
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
( Springer-Verlag France , 2018 , Article Review)Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ... -
A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
( Elsevier B.V. , 2016 , Article)Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ... -
A study to investigate the impact of a blended learning teaching approach to teach pharmacy law
( Wiley-Blackwell Publishing Ltd , 2019 , Article)Objective To describe the implementation and assess the effect of a blended learning approach to teach pharmacy law. Methods Twenty didactic pharmacy law lectures were redeveloped to 9 h of flipped classroom sessions. ... -
A survey on the awareness and attitude of pharmacists and doctors towards the application of pharmacogenomics and its challenges in Qatar
( John Wiley & Sons, Ltd. , 2015 , Article)RATIONALE, AIMS AND OBJECTIVES: Pharmacists are expected to play an important role in applying pharmacogenomics discoveries to patient care. Despite the increased attention to genetic research in Qatar, clinicians' attitudes ... -
A Survey on the Awareness and Attitude of Physicians on Direct Oral Anticoagulants in Qatar
( SAGE Publications Inc. , 2018 , Article)Direct oral anticoagulants (DOACs) are more commonly prescribed since their introduction. Reports on inappropriate prescribing have been observed which may indicate poor awareness on these agents. In this study, we aim to ... -
A Systematic Review of Antimicrobial Stewardship Interventions in the Emergency Department
( SAGE Publications Inc. , 2017 , Article Review)Background/Objective: To improve antimicrobial utilization, development and implementation of antimicrobial stewardship programs in the emergency department (ED) has been recommended. The primary objective of this review ... -
A systematic review of audience response systems in pharmacy education
( Elsevier Inc. , 2019 , Article Review)Background: Audience response systems (ARS) are increasingly being used to support learning and assessment. Despite widespread use, the effects on educational outcomes and student learning are largely unknown. The objective ... -
A systematic review of pharmaceutical pricing policies in developing countries
( Blackwell Publishing Ltd , 2017 , Article Review)Objective A systematic review was conducted to summarize government strategies aimed at controlling pharmaceutical prices in developing countries and their effects on relevant outcomes, and to qualitatively analyse eligible ... -
A systematic review of the outcome data supporting the Healthy Living Pharmacy concept and lessons from its implementation
( Public Library of Science , 2019 , Article)Background The Healthy Living Pharmacy (HLP) project, launched in England, UK in 2009 was a novel approach of introducing public health services within community pharmacy to tackle local health inequalities. A national ...
