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Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
(
Hindawi
, 2017 , Article)
Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, ...
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
(
Hamad bin Khalifa University Press (HBKU Press)
, 2016 , Conference Paper)
Background and Objectives: Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates ...
Role of methylglyoxal in diabetic cardiovascular and kidney diseases: Insights from basic science for application into clinical practice
(
Bentham Science Publishers
, 2018 , Other)
Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. ...