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Now showing items 11-20 of 53
The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.
(
MDPI
, 2019 , Article Review)
Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ...
Perspectives of pharmacy students, pharmacy academics and practicing pharmacists on interprofessional education and collaborative practice: a comprehensive systematic review protocol
(2016 , Article Review)
Review question/objective
The objective of this systematic review is to examine the perspectives, attitudes, views and experiences of pharmacy students, pharmacy academics and practicing pharmacists towards interprofessional ...
Cisplatin based therapy: The role of the mitogen activated protein kinase signaling pathway
(
BioMed Central Ltd.
, 2018 , Article Review)
Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced ...
The impact of genetic and non-genetic factors on warfarin dose prediction in MENA region: A systematic review
(
Public Library of Science
, 2016 , Article Review)
Background Warfarin is the most commonly used oral anticoagulant for the treatment and prevention of thromboembolic disorders. Pharmacogenomics studies have shown that variants in CYP2C9 and VKORC1 genes are strongly and ...
Factors associated with medication adherence among patients with diabetes in the Middle East and North Africa region: A systematic mixed studies review
(
Elsevier
, 2017 , Article Review)
Multiple systematic reviews were conducted investigating factors associated with medication adherence worldwide. However, investigations from the Middle East and North Africa (MENA) region were largely underrepresented in ...
Cancer-Associated Venous Thromboembolism
(
Springer Healthcare
, 2016 , Article Review)
Cancer patients are at high risk for venous thromboembolism (VTE) which is considered the second leading cause of death among this population. Both cancer and cancer treatment increase this risk. Since the risk of VTE is ...
A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
(
Springer-Verlag France
, 2017 , Article Review)
Genetic variability in drug-metabolizing enzymes and drug transporters is known to influence the pharmacokinetics of many drugs. Antimalarial drugs are a class of agents known to utilize metabolic and elimination pathways ...
Review of National and International Accreditation of Pharmacy Programs in the Gulf Cooperation Council Countries.
(
Aacp American Association
, 2018 , Article Review)
To compare the different philosophies, emphases and processes of national and international accreditation paths available to pharmacy programs in Gulf Cooperation Council (GCC) countries. To identify engagement of GCC ...
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
(
Springer-Verlag France
, 2018 , Article Review)
Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ...
Clinical Pharmacokinetics and Drug Interactions of Doravirine
(
Springer-Verlag France
, 2018 , Article Review)
Doravirine is a new HIV-1 non-nucleoside reverse transcriptase inhibitor that has demonstrated a good efficacy and safety profile in clinical trials. It has a therapeutic profile that makes it an attractive option for ...