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Medicines Pricing Policy and Strategies in Developing Countries: A Review
(
Elsevier Inc.
, 2018 , Book chapter)
Developing countries are still facing high out-of-pocket expenditure and low access to medicines despite the various efforts undertaken by international organizations to enhance the availability of essential medicines and ...
Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells
(
Taylor and Francis Ltd
, 2018 , Article)
In this study the anticancer activity of paclitaxel-loaded nano-liposomes on glioma cell lines was investigated. Soya phosphatidylcholine:cholesterol (SPC:Chol), hydrogenated soya phosphatidylcholine:cholesterol (HSPC:Chol) ...
A Review of the Clinical Pharmacokinetics and Pharmacodynamics of Isavuconazole
(
Springer-Verlag France
, 2018 , Article Review)
Invasive fungal infections are a major cause of morbidity and mortality, especially for immunocompromised patients. Treatment options are few and most are limited by safety and formulation concerns. Isavuconazole is a new ...
Poisoning emergency visits among children: a 3-year retrospective study in Qatar
(
BioMed Central
, 2015 , Article)
Background
Poisoning in toddlers and infants is almost always unintentional due to their exploratory behavior, which is different from adults. The prevalence and background of childhood poisoning in Qatar is still unknown. ...
Obesity-induced changes in kidney mitochondria and endoplasmic reticulum in the presence or absence of leptin
(
American Physiological Society
, 2015 , Article)
We investigated obesity-induced changes in kidney lipid accumulation, mitochondrial function, and endoplasmic reticulum (ER) stress in the absence of hypertension, and the potential role of leptin in modulating these ...
Does pharmacist-supervised intervention through pharmaceutical care program influence direct healthcare cost burden of newly diagnosed diabetics in a tertiary care teaching hospital in Nepal: a non-clinical randomised controlled trial approach
(
Tehran University of Medical Sciences
, 2016 , Article)
Background
Cost is a vital component for people with chronic diseases as treatment is expected to be long or even lifelong in some diseases. Pharmacist contributions in decreasing the healthcare cost burden of chronic ...
Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
(
Hindawi Publishing Corporation
, 2018 , Article)
Over the last decade, the zebrafish (Danio rerio) has emerged as amodel organismfor cardiovascular research.Zebrafish have several advantages over mammalian models. For instance, the experimental cost of using zebrafish ...
Phloretin attenuates STAT-3 activity and overcomes sorafenib resistance targeting SHP-1-mediated inhibition of STAT3 and Akt/VEGFR2 pathway in hepatocellular carcinoma
(
BioMed Central Ltd.
, 2019 , Article)
Background: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Phloretin (PH) possesses anticancer, antitumor, and hepatoprotective effects, however, the effects and potential mechanisms of phloretin ...
Greensporone A, a fungal secondary metabolite suppressed constitutively activated AKT via ROS generation and induced apoptosis in leukemic cell lines
(
MDPI AG
, 2019 , Article)
Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. ...
Extent of extemporaneous compounding and pattern of prescribing and use of extemporaneous medicines in a developing setting
(
Blackwell Publishing Ltd
, 2019 , Article)
Objectives: To determine the extent of extemporaneous compounding, the prescribing pattern and use of extemporaneous medicines in a developing setting like Nigeria. Methods: A cross-sectional assessment was conducted at ...